Imran Idrees teaching hospital sialkot
Sialkot, Punjab Province, 40100, Pakistan
Location status: Recruiting
Location contact
Misdaq Batool, MS PT
CONTACT
Nida Khalid, MS PT
PRINCIPAL_INVESTIGATOR
Recruiting
NCT Number: NCT07713017
Combined Effects of Aerobic Exercise and Strength Training Among Post CABG Patients
Title of study Combined effects aerobic exercise and strength training on functional capacity, cardiorespiratory fitness and quality of life with cardiac rehabilitation phase II among post CABG patients Objective (s) of the study To investigate the combined effects of aerobic exercise and strength training on functional capacity, cardiorespiratory fitness and quality of life with cardiac rehabilitation phase II among post CABG patients.
Methodology (Design, sample size, sampling technique, Study setting, inclusion and exclusion criteria and Tool) Design: Randomized Controlled Trial Sample Size: 42 patients Sampling Technique: Convenient sampling technique will be used for selection of patient after that simple random sampling technique will be used for randomization among groups Study Setting: Hospital Setting SF-12, 6-min walk test, VO2 max, step test This study will not harm any fundamental rights of the patients and will consider and respect the preferences of patients.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
30 year–60 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
About this study
Coronary artery bypass grafting (CABG) is a common surgical procedure for coronary artery disease (CAD). Post-CABG patients often experience decreased functional capacity, muscle strength, and quality of life due to prolonged bed rest, surgical trauma, and underlying cardiovascular disease. Cardiac Rehabilitation after coronary artery bypass graft surgery is necessary to prevent complications, improve functioning, and alleviate symptoms. Aerobic exercises and strength training are used in CR, but their combined effects on post-CABG patients are not well understood. The objective of this study will be to investigate the combined effects of aerobic exercise and strength training on functional capacity, cardiorespiratory fitness and quality of life with cardiac rehabilitation phase II among post CABG patients.
Study design will be randomized controlled trial. 42 patients will be included in study. Data will be collected from Imran Idrees hospital, Sialkot. Convenient sampling technique will be used for selection of patient after that simple random sampling technique for randomization among groups. Study will be conducted within 10 months after approval of synopsis. The SF-12 questionnaire will be used for quality of life, 6-minute walk test for functional capacity, step test and VO2max for cardiorespiratory fitness. Both genders aged between 30 to 60 years with stable cardiovascular condition and no other comorbidities will be included in this study. Participants with any musculoskeletal or neurological impairment and symptoms of significant myocardial ischemia, including chest pain and any history of fracture or surgery will be excluded from this study. Patients will be divided in to two groups. Group A will be assigned aerobic exercise and Group B will be assigned aerobic exercise and strength training. Pre and post values for functional capacity, cardiorespiratory fitness and quality of life will be recorded. Data will be analyzed by using SPSS version 24. After testing the Normality of data by applying Shapiro-wilk test, paired sample t-test/ independent t-test / Anova test to find which technique will be more beneficial for post CABG patients.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Both genders (male, female)
- Patient who underwent a successful CABG (no complications during surgery and/or in the following weeks)
- Patients willing to participate in the phase II cardiac rehabilitation program.
- Age between 30 to 60 years
- Patients having no impairment in the musculoskeletal system
Exclusion criteria
- Patients with unstable congestive heart failure and symptoms of significant myocardial ischemia, including chest pain
- Patients with uncontrolled diabetes mellitus or hypertension.
- Patients with any motor or neurological impairment
- Patients with severe disturbance of consciousness, having an orthopedic problem and critical limb ischemia
Treatment and study plan
Aerobic Exercise
BehavioralAerobic Exercise Plan:
- Warm-up (5 minutes): - Light arm movements (e.g., arm circles, shoulder rolls) - Dynamic stretching (e.g., arm swings)
- Aerobic Exercise (20-30 minutes): - Arm cycle ergometer - Intensity: Moderate (40-60% of maximum heart rate reserve) - Frequency: 2-3 times per week
- Cool-down (5-10 minutes): - Static stretching (e.g., bicep, triceps, chest muscles)
Aerobic Exercise and strength training
Behavioral- Warm-up (5-10 minutes): - Light cardio (e.g., walking, jogging in place) - Dynamic stretching (e.g., arm circles, leg swings)
- Aerobic Exercise (10-20 minutes): - Arm cycle ergometer - Intensity: Moderate (40-60% of maximum heart rate reserve) - Frequency: 2-3 times per week
- Resistance Training (10-15 minutes): - Upper extremity exercises using resistance bands or light dumbbells - 2-3 sets of 8-12 repetitions per exercise - Intensity: 30-70% of 1RM - Frequency: 2-3 times per week
Cool-down (5-10 minutes): - Static stretching (e.g., bicep, triceps, chest muscles)
Primary outcomes
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Six-Minute Walk Test (6MWT)
Time frame: 5 weeks
The six-minute walk test (6MWT) is a simple test that objectively evaluates a patient's functional capacity. This simple walk test is particularly applicable in the CAD population due to the risk of acute cardiac events associated with the gold standard maximal exercise testing for assessing functional capacity. The 6MWT requires a 30-m, flat, hard walking path, a stopwatch, a lap counter and two cones to mark the turning points. The patients were instructed to walk as far as possible along the pathway, in 6 minutes. During the test encouragement was not given and only asked about their conditions. At the end, total walked distance was measured and recorded
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Step test
Time frame: 5 weeks
The 6 min step test is a safe, valid, sensitive, and reproducible tool for evaluating cardiorespiratory fitness. The 6MST was shown to be a safe and reliable field test to assess exercise tolerance in a sample of very deconditioned adults at risk of CVD
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Vo2 max
Time frame: 5 weeks
Vo2 max was estimated using a graded exercise test. Oxygen consumption was measured using metabolic gas analyzer. In this research VO2 Max will be measured through a submaximal 6 mint walk test
Secondary outcomes
-
SF-12 Questionnaire
Time frame: 5 weeks
The SF-12 are multi-item generic health surveys intended to measure general health. The SF 12 is a shorter version of the SF-36 and uses only 12 questions to measure functional health and well-being from the patient's perspective. SF-12 were first published in 1992 and 1996, respectively, with the revised versions of both questionnaires published in 2000. SF-12 measure 8 health domains: physical functioning, role physical, bodily pain, general health, vitality, social functioning, role emotional, and mental health. The SF-12 consists of 12 items: 2 items on physical functioning, 2 items on role physical, 1 item on bodily pain, 1 item on general health, 1 item on vitality, 1 item on social functioning, 2 items on role emotional, and 2 items on mental health.
Study contacts
Contact information is provided by the study sponsor or research team.
Misdaq Batool, MS PT
CONTACT
Muhammad Iqbal Tariq, pHD
CONTACT
Sponsors and collaborators
Lead sponsor
Riphah International University
Other
Registry information
Official study title
Combined Effects of Aerobic Exercise and Strength Training on Functional Capacity, Cardiorespiratory Fitness and Quality of Life With Cardiac Rehabilitation Phase II Among Post CABG Patients
Important dates
- Study start
- 2026
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Jul 20, 2026
- Registry last updated
- Jul 20, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.