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Completed

NCT Number: NCT03865004

Combination Trial of Intravenous Paracetamol - Morphine for Treating Acute Renal Colic in Emergency Setting: An Optimum Treatment

This randomized, placebo-controlled trial evaluated the analgesic efficacy and safety of intravenous morphine-paracetamol combination and morphine-dexketoprofen combination morphine for the optimum treatment of renal colic. Combination of IV morphine and paracetamol is as effective and rapid as combination of IV Morphine and IV dexketoprophen for optimum treating of renal colic.

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Key information

Conditions

Renal Colic Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Renal colic patients -

Exclusion criteria

Not renal colic patients

-

Treatment and study plan

Paracetamol+Morphine

Drug

1gr paracetamol plus 0.1 mg/kg morphine were performed simultanously

Other names: Parol

Dexketoprofen plus Morphine

Drug

Intravenous 75 mg Dexketoprofen plus 0,1 mg/kg morphine were performed simultanously

Other names: Arveles

Placebo plus Morphine

Drug

100 cc NaCl plus 0.1 mg/kg morphine were performed simultanously

Other names: SF

Primary outcomes

  1. pain reductions in VAS scores during the 60th and 90th minutes

    Time frame: 60 minutes

Secondary outcomes

  1. Need for rescue analgesic

    Time frame: 30 minutes

Sponsors and collaborators

Lead sponsor

Akdeniz University

Other

Registry information

Official study title

Paracetamol Plus Morphine in ED

Important dates

Study start
2015
Primary completion
2016
Study completion
2018
First posted
Mar 6, 2019
Registry last updated
Mar 6, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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