Combination Therapy With Atelocollagen in Epidural Nerve Block

Inclusion criteria

• Patients scheduled for epidural nerve block for lower back pain
• Patients over 21 years of age
• Back pain lasting more than 6 months
• Patients with ineffective or insignificant effects of conventional drugs and nerve block for back pain
• Patients with spinal stenosis or disc herniation at the lumbar 4-5 or lumbar 5-sacral 1 level on MRI, and the cross-sectional area of the multifidus muscle at the lesion site is less than 5 cm2 when measured by ultrasound.

Exclusion criteria

• When the degree of low back pain is 3 points or less on the 11-scale numeric rating scale (hereafter NRS)
• If lower back pain has rapidly worsened within the last week
• If you have other diseases that may cause low back pain: osteoarthritis of the hip joint, cancer, inflammatory arthritis, spondylitis, fibromyalgia, complex regional pain syndrome, herpes zoster, postherpetic neuralgia, etc.
• When a diagnostic epidural nerve block is planned
• In the case of receiving conservative treatment, procedure, or surgery other than oral drugs such as epidural nerve block or proliferation treatment for the treatment of lower back pain within 4 weeks of screening
• When the low back pain assessed by NRS decreased by more than 50% after epidural nerve block in screening
• If back surgery is planned within 3 months of the procedure
• When NRS and ODI measurements cannot be made
• When collagen injection is contraindicated (eg when allergic to swine)
• Pregnant women
• If you cannot read or agree to the consent form
• If you are unable to sign the consent form yourself