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NCT Number: NCT06973473

Combination Therapy of Imiquimod 5%Cream and Cryotherapy vs Monotherapy for Common Warts:Randomized Comparative Trial.

To assess the clinical efficacy and safety of topical imiquimod 5% cream combined with cryotherapy versus either of theme alone for the treatment of common warts by clinical and dermoscopic assessments.

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Key information

Conditions

Warts DNA Virus Infections Infections Papillomavirus Infections Skin Diseases Skin Diseases, Infectious Skin Diseases, Viral Skin and Connective Tissue Diseases Tumor Virus Infections Virus Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

About this study

Topical Imiquimod 5% cream Combined with Cryotherapy Versus either of them alone in Treatment of Common Warts: A prospective Randomized Comparative Trial

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with common warts diagnosed clinically and by dermoscopy.
  • Patients older than 18years old.

Exclusion criteria

  • Pregnancy and lactation.
  • Immunosuppression or being under any kind of treatment causing
  • absolute or relative immunosuppression.
  • Patients with chronic systemic diseases.
  • All cases of bleeding tendency or using anticoagulants.
  • Concurrent use of systemic or topical treatments of warts in the last 4 weeks.

Treatment and study plan

Primary outcomes

  1. Complete clearance rate of common warts.

    Time frame: 12 weeks

    Assessment of complete warts clearance rate at 12weeks to evaluate the efficacy of combination therapy ( imiquimod5%cream+cryotherapy ) compared to topical imiquimod5%cream alone or cryotherapy alone in patients with common wart.

Study contacts

Contact information is provided by the study sponsor or research team.

Eman Fathy Ahmed Lecturer of Dermatology, Venereology and Andrology Faculty of

CONTACT

[email protected]

00201002258614

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Aprospective,Randomized,Comparative Clinical Trial of Combination Therapy of Imiquimod 5%Cream and Cryotherapy vs Monotherapy for Common Warts.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 15, 2025
Registry last updated
May 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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