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OpenTrials
Completed

NCT Number: NCT02885103

Combination of NHF and Nebulizer on Lung Function in COPD

This study will prove to concept of effectiveness of NHF in combination with a nebulizer on reversibility of lung function in COPD patients.

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Key information

Conditions

Chronic Obstructive Pulmonary Disease Chronic Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Respiratory Medicine

Leipzig, Saxony, 04103, Germany

About this study

Patients will inhale on day 1 with a nebulizer and on another day with combination of nebulizer an NHF in a randomised order.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • stable disease
  • COPD

Exclusion criteria

  • exacerbation
  • right heart decompensation
  • acute respiratory insufficiency
  • acute disease

Treatment and study plan

Nasal high flow (NHF)

Device

NHF will be combinated with a nebulizer. Inhalation will be done on nasal cavity.

Nebulizer

Device

Inhalation will be done will Nebulizer and via mouth

Primary outcomes

  1. changes in forced expiratory volume in 1s (FEV1)

    Time frame: 45 minutes

    litre

  2. changes in breath way resistance (Rtot)

    Time frame: 45 min

Sponsors and collaborators

Lead sponsor

University of Leipzig

Other

Registry information

Official study title

Effect of Nasal Highflow in Combination With a Nebulizer on Reversibility in Lung Function in Patients With COPD

Acronym: AEROFLOW

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Aug 31, 2016
Registry last updated
Mar 27, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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