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Completed

NCT Number: NCT05169528

Colorectal Cancer Prehabilitation in Changi General Hospital

Cancer prehabilitation typically involves multiple pre-op visits. The investigators aim to assess the impact of their novel model, a "one-stop "service by a small, "levelled-up" core team on newly diagnosed colorectal cancer patients planned for surgery.

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Key information

Conditions

Colorectal Cancer Colonic Diseases Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases

Age range

21 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Changi General Hospital

Singapore, 529889

About this study

Objective Cancer prehabilitation typically involves multiple pre-op visits. The investigators aim to assess the impact of their novel model, a "one-stop "service by a small, "levelled-up" core team on newly diagnosed colorectal cancer patients planned for surgery.

Design This is a before-after trial in a tertiary public hospital in Singapore, involving all newly diagnosed colorectal cancer patients planned for surgery who are referred to the Cancer Prehabilitation Program. The primary outcome measure is the 6-minute-walk-test. Others include physical, psychological, quality-of-life and post-operative measures, and patient-satisfaction-surveys, taken at baseline, pre-operatively (post-prehabilitation), and 3-months-post-operatively.

Keywords: Colorectal; Cancer Prehabilitation; Novel; Model of Care

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All newly diagnosed colorectal cancer patients planned for surgery in Changi General Hospital, Singapore

Exclusion criteria

  • Patients' refusal to participate

Treatment and study plan

Colorectal Cancer Prehabilitation Programme

Other

Assessment and Interventions involving the Prehabilitative domains of medical optimisation, exercise prescription, nutrition and mental health optimisation

Primary outcomes

  1. 6-minute-walk-test

    Time frame: Baseline

    Distance walked in 6 minutes under standardised conditions

  2. 6-minute-walk-test

    Time frame: Pre-Operatively (after prehabilitation)

    Distance walked in 6 minutes under standardised conditions

  3. 6-minute-walk-test

    Time frame: Post-Operatively (3 months)

    Distance walked in 6 minutes under standardised conditions

Secondary outcomes

  1. 30-second-sit-to-stand-test

    Time frame: Baseline

    Number of repetitions of sit-to-stand within 30 seconds

  2. 30-second-sit-to-stand-test

    Time frame: Pre-Operatively (after prehabilitation)

    Number of repetitions of sit-to-stand within 30 seconds

  3. 30-second-sit-to-stand-test

    Time frame: Post-Operatively (3 months)

    Number of repetitions of sit-to-stand within 30 seconds

  4. Hospital Anxiety and Depression Scale

    Time frame: Baseline

    Divided into Anxiety (0-21 points) and Depression scale (0-21 points), the higher the worser

  5. Hospital Anxiety and Depression Scale

    Time frame: Pre-Operatively (after prehabilitation)

    Divided into Anxiety (0-21 points) and Depression scale (0-21 points), the higher the worser

  6. Hospital Anxiety and Depression Scale

    Time frame: Post-Operatively (3 months)

    Divided into Anxiety (0-21 points) and Depression scale (0-21 points), the higher the worser

  7. EuroQol- 5 Dimension

    Time frame: Baseline

    Health Score (visual analogue scale from 0-100), the higher the better

  8. EuroQol- 5 Dimension

    Time frame: Post-Operatively (3 months)

    Health Score (visual analogue scale from 0-100), the higher the better

  9. Post-Operative Hospital Length of Stay

    Time frame: From Date of Admission for Surgery till Date of Discharge, assessed up to 100 weeks

    Post-Operative Hospital Length of Stay

  10. 30-Day Post-Operative Major Complications

    Time frame: From Surgery till 30 Days Post-op

    30-Day Post-Operative Major Complications

  11. 30-Day Post-Operative Readmission Rates

    Time frame: From Surgery till 30 Days Post-op

    30-Day Post-Operative Readmission Rates

  12. 30-Day Post-Operative Mortality

    Time frame: From Surgery till 30 Days Post-op

    30-Day Post-Operative Mortality

  13. Patient Satisfaction Survey

    Time frame: Pre-Operatively (after prehabilitation)

    Patient Satisfaction Survey

  14. Patient Satisfaction Survey

    Time frame: Post-Operatively (3 months)

    Patient Satisfaction Survey

Sponsors and collaborators

Lead sponsor

Changi General Hospital

Other

Registry information

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Dec 27, 2021
Registry last updated
Dec 27, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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