Color-dependent Melatonin Suppression

The purpose of this study is to examine the effects of complex, broad-band spectra light on the production of melatonin in humans.

Completed

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Key information

Conditions

Melatonin

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

VA Palo Alto Health Care System

Palo Alto, California, 94304, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Stable health
Normal color vision
Normal hearing
18-35 years old

Exclusion criteria

Significant depressive symptoms
Pregnant or nursing
Ocular pathologies
Unstable or severe medical or psychiatric condition
Extreme morning/evening type
Regular smoker
Use of medications that impact ocular function
Alcohol use disorder
Use of illegal drugs
Irregular use of antihistamines, antidepressants, or sleeping medications

Treatment and study plan

Light - standard

Device

Light will be given during the night to determine its effects on melatonin suppression. This light will be an LED with standard spectral distribution

Light - alternate

Device

Light will be given during the night to determine its effects on melatonin suppression. This light will be an LED with an altered spectral distribution (different color)

Primary outcomes

Melatonin suppression

Time frame: 4 Hours

The amount of declination of salivary melatonin concentrations between the start of the light and the end of the light (4 hours later) will be compared between the conditions.

Sponsors and collaborators

Lead sponsor

VA Palo Alto Health Care System

Fed

Registry information

Important dates

Study start: 2016
Primary completion: 2017
Study completion: 2017
First posted: Oct 18, 2016
Registry last updated: Jan 5, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed