Skip to main content
OpenTrials
Completed

NCT Number: NCT03361904

Colonoscopic Adenoma and Advanced Neoplasia Detection Rates According to Age

Current recommendations for colonoscopy screening programs usually involve patients older than 50 years of age. However, little is known about polyp or adenoma detection rates under 50. We compared these detection rates according to age in a large series of patients in common practice.

Methods: All colonoscopies performed in 2016 in our unit were prospectively recorded. We determined adenoma detection rate (ADR), polyp detection rate (PDR), mean number of polyps (MNP), and advanced neoplasia detection rate (ANDR).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Colonic Polyp Age Colon Adenoma Colon Cancer Colonic Diseases Colonic Neoplasms Colonic Polyps Colonoscopy Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Intestinal Polyps Neoplasms Neoplasms by Site Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Polyps

Age range

15 year–99 year

Sex eligibility

All sexes

Study type

Observational

About this study

Patients All consecutive patients who were scheduled for colonoscopy were included. Exclusion criteria were: patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).

Data collection The following data have been prospectively collected: age, gender, indication for colonoscopy, preparation procedure and quality of the preparation (assessed by the Boston Bowel Preparation Scale; BBPS) [19-20], caecal intubation (yes/no), withdrawal time, number and size of polyps and polyp histopathology.

All clinical data were collected during the procedure by a nurse and an endoscopist on a dedicated software. The database was then supplemented by the Clinical Research Associate for histopathological data.

We determined adenoma detection rate (ADR; percentage of colonoscopies with at least one adenoma), polyp detection rate (PDR: percentage of colonoscopies with at least one polyp), mean number of polyps per colonoscopy (MNP), large polyp detection rate (LPDR; percentage of colonoscopies with at least one polyp of 1 cm or more) and advanced neoplasia detection rate (ANDR: percentage of colonoscopies with at least one advanced neoplastic lesion as defined below).

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All consecutive patients who were scheduled for colonoscopy were included.

Exclusion criteria

  • patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).

Treatment and study plan

colonoscopy

Procedure

Total colonoscopy : All consecutive patients who were scheduled for colonoscopy were included. Exclusion criteria were: patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).

Primary outcomes

  1. Adenoma detection rate according to age

    Time frame: during colonoscopy

    ADR <30yo, in 30-34 yo, in 35-39yo, in 40-44yo, in 45-49yo, in 50-54yo, in 55-59yo, in 60-64yo, in 65-69 yo, in 70-74yo, in 75-79yo and >79yo intervals

  2. Advanced Neoplasia Detection rate according to age

    Time frame: during colonoscopy

    ANDR <30yo, in 30-34 yo, in 35-39yo, in 40-44yo, in 45-49yo, in 50-54yo, in 55-59yo, in 60-64yo, in 65-69 yo, in 70-74yo, in 75-79yo and >79yo intervals

Secondary outcomes

  1. Age

    Time frame: during colonoscopy

    years old

  2. Gender

    Time frame: during colonoscopy

    Male or Female

  3. Indication for colonoscopy

    Time frame: during colonoscopy

    pain / screening/ familial or personal history of polyp or cancer

  4. quality of the preparation

    Time frame: during colonoscopy

    Boston Bowel Preparation Scale Segment Score Description 0: unprepared colon segment with mucosa not senn due to solid stool that cannot be cleared

    • Portion of mucosa of the colon segment seen, but other areas of the colon segment are not well seen due to staining, residual stool, and/or opaque liquid
    • minor amount of residual staining, small fragments of stool, and/or opaque liquid, but mucosa of colon segments is seen well
    • entire mucosa of colon segment seen well, with no residual staining, small fragments of stool or opaque liquid

    Total score is a summation of scores from three segments of the colon Score is from 0 to 9

  5. Caecal intubation

    Time frame: during colonoscopy

    Y/N

  6. Withdrawal time

    Time frame: during colonoscopy

    in seconds

Sponsors and collaborators

Lead sponsor

Société Française d'Endoscopie Digestive

Other

Registry information

Official study title

Adenoma and Advanced Neoplasia Detection Rates Increase From 45 Year of Age: Results of a Monocentric One-year Observational Cohort Study on 6027 Colonoscopies

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Dec 5, 2017
Registry last updated
Dec 5, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.