Collection of Plasma Samples for Squamous Cell Carcinoma of the Head and Neck Patients

The investigators will collect plasma samples at baseline, during treatment, and at progression.

Recruiting

Interested in participating?

Key information

Conditions

Squamous Cell Carcinoma of the Head and Neck Carcinoma Carcinoma, Squamous Cell Head and Neck Neoplasms Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Squamous Cell Carcinoma of Head and Neck

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Clinique Saint-Pierre, Ottignies, Brabant Wallon, Belgium

About this study

In this study, the investigators will collect plasma samples at baseline, during treatment, and at progression. This plasma bank will be used to study the potential value of some biomarkers to predict treatment activity or resistance to cetuximab or other targeted agents

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients treated with radiation therapy and cetuximab according to Bonner et al
patients treated with cetuximab in combination with chemotherapy according to Vermorken et al.
patients treated with a molecular targeted agent as a part of a clinical study

Exclusion criteria

patients with another type of head and neck cancer
patients non treated with targeted therapies

Treatment and study plan

plasma samples

Other

Plasma samples at baseline (and one whole blood sample) and at every radiological evaluations

Primary outcomes

Prospective storage of plasma samples of patients treated with cetuximab or other targeted agents

Time frame: one year after the collection

All the analyses will be done when we have enough of collected samples

Study contacts

Contact information is provided by the study sponsor or research team.

Jean-Pascal Machiels, MD, PhD

CONTACT

[email protected]

0032 2 764 ext. 5457

Séverine Carlier, MD

CONTACT

[email protected]

0032 2 764 ext. 47849

Sponsors and collaborators

Lead sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Other

Registry information

Official study title

Prospective Collection of Plasma Samples From Patients Treated With Molecular Targeted Therapies for Squamous Cell Carcinoma of the Head and Neck

Important dates

Study start: 2013
Primary completion: 2033
Study completion: 2033
First posted: May 15, 2014
Registry last updated: Dec 11, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Recruiting