Collection of Information to Better Understand Young Onset Colorectal Cancer

The purpose of this registry study is to create a database-a collection of information-for better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this database to learn more about how young onset colorectal cancer may be similar to or different from colorectal cancer that is diagnosed later in life. Researchers will also use information from the database for current and future research on young onset colorectal cancer.

Recruiting

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Key information

Conditions

Colorectal Cancer Colonic Diseases Colorectal Carcinoma Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Memorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge, New Jersey, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Participant Inclusion Criteria for database and questionnaire (YOGI)

Histological or cytological diagnosis of gastrointestinal cancer
18 - 49 years old at time of consent
No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only)
No history of inflammatory bowel disease (stool collection cohort only)
No prior diagnosis of gastrointestinal cancer (stool collection cohort only)

Participant Inclusion Criteria for database and questionnaire (Controls)

Histological or cytological diagnosis of colorectal adenocarcinoma
No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation)
Age 50 or older at time of consent
No Known hereditary CRC or other cancer predisposition syndrome
No history of inflammatory bowel disease
No prior diagnosis of CRC

Treatment and study plan

Risk Factor Questionnaire

Other

Participants, both cases and controls, will complete the CYOC risk factor questionnaire, preferably at the time of first visit

Other names: CYOC Risk Factor Questionnaire

Primary outcomes

Establish a prospective database of patients with Young Onset Colorectal Cancer

Time frame: 1 year

from diagnosis through survivorship

Study contacts

Contact information is provided by the study sponsor or research team.

Andrea Cercek, MD

CONTACT

[email protected]

646-888-4189

Rona Yaeger, MD

CONTACT

[email protected]

646-888-5109

Sponsors and collaborators

Lead sponsor

Memorial Sloan Kettering Cancer Center

Other

Registry information

Official study title

Young Onset Gastrointestinal Cancer Prospective Registry

Important dates

Study start: 2020
Primary completion: 2026
Study completion: 2026
First posted: Jul 28, 2020
Registry last updated: Feb 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting