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Active, Not Recruiting

NCT Number: NCT03288805

Cohort Study in South China

Healthy Chinese residents from South China will be recruited and followed up for at least 4 years to evaluate the association between climate, diet and lifestyle and risks for the development of chronic diseases. Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of chronic diseases will be investigated during follow-up.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Chronic Disease Disease Attributes Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

35 year–74 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sun Yat-Sen University

Guangzhou, Guangdong, 510080, China

About this study

110,000 adult Chinese (35 to 74 years old) without chronic diseases and major disability who have been living in South China including Guangdong, Fujian, Guangxi and Hainan for more than 5 years will be recruited. All participants will be prospectively followed up for the incidence of chronic diseases (stroke, coronary heart disease, malignant neoplasms, chronic obstructive pulmonary diseases, diabetes and hypertension) and their risk factors (impaired glucose tolerance and obesity). Information about socio-demographic, diet, lifestyle, psychological status, medical history and current medication will be collected by questionnaires. Physical examinations including height, weight, waist and hip circumferences, blood pressure, fat mass and vital capacity will be conducted. Besides, blood, urine and fecal samples will be collected for further analysis. Annual meteorological data throughout the study period will also be collected. The associations between climate, diet and lifestyle and risks for chronic diseases will be evaluated.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult Chinese (35-74 years old) who have been living in South China including Guangdong, Fujian, Guangxi and Hainan provinces for more than 5 years.

Exclusion criteria

  • any subject diagnosed with stroke, coronary heart disease, malignancy, chronic obstructive pulmonary disease, diabetes and hypertension.
  • any subject who suffer from major disability and cannot participate in the study.

Treatment and study plan

Primary outcomes

  1. Incidence of chronic disease

    Time frame: 4 years

    Incidence of chronic disease, including stroke, coronary heart disease, cancer, chronic obstructive pulmonary disease, diabetes and hypertension

Secondary outcomes

  1. Risk factors for chronic diseases

    Time frame: 4 years

    Incidence of impaired glucose tolerance and obesity

Sponsors and collaborators

Lead sponsor

Min Xia

Other

Collaborators

  • Fujian Medical University
  • Guangxi Medical University
  • Guangzhou Medical University
  • Guangzhou No.12 People's Hospital
  • Hainan Medical College
  • Shenzhen Fifth People's Hospital
  • The First Affiliated Hospital of Xiamen University

Registry information

Official study title

Prospective Cohort Study of Chronic Diseases in South China

Important dates

Study start
2017
Primary completion
2030
Study completion
2030
First posted
Sep 20, 2017
Registry last updated
May 5, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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