University of Missouri
Columbia, Missouri, 65212, United States
NCT Number: NCT04899089
Older adults (60+ years of age) who meet criteria for mild cognitive impairment and insomnia will be randomly assigned to cognitive training or trivia training and will complete measures of anxiety, sleep, cognition (objective, self-efficacy), and arousal at baseline, and post-intervention. For cognitive training, participants will be provided with login information to access the computerized training, and will complete 8 weeks (45 mins 3x/week) of cognitive training. For trivia training, participants will receive weekly emails that contain trivia assignments that they will complete for 8 weeks (45 mins 3x/week). We will evaluate short-term (i.e., post-training) effects of the two training conditions on subjective anxiety, sleep, arousal, and subjective and objective cognition.
Looking for future studies?
Notify Me60 year and older
All sexes
Interventional
Not applicable
Columbia, Missouri, 65212, United States
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The computerized training exercises and brain games help stimulate cognitive functions while providing real-time monitoring on the evolution of participants' skills.
The computerized trivia training asks participants to answer general questions related to pop culture, science, geography, etc. Participants can use online sources to search for answers and will be provided feedback on their accuracy.
Time frame: Up to 10 weeks
Complete computerized tasks. These tasks will measure cognitive functions (e.g., processing speed, attention, memory).
Time frame: Up to 10 weeks
A 25 item questionnaire. Participants rate from 0 (never) to 4 (very often) frequency of cognitive errors. Higher scores indicate lower cognitive self-efficacy.
Time frame: Up to 10 days
Electronic Daily Sleep Diaries. Online diaries completed each morning (~5 mins) during the study. Diaries measure sleep onset latency, wake time after sleep onset, total sleep time, and sleep quality.
Time frame: Up to 10 weeks
Brief self-report measure of current perception of insomnia symptom severity, distress and daytime impairment. Commonly used in insomnia treatment outcome research.
Time frame: Up to 10 weeks
Single night objective sleep recording via a wrist worn device.
Time frame: Impact of game related experience will be measured at baseline
CorSense monitor assessed 5 min heart rate recordings both at rest. Time index variables: SDNN (standard deviation of normal to normal heartbeat intervals)
Time frame: Up to 10 weeks
Inventory that asks respondents to rate how true 20 self-descriptive statements (e.g., I feel calm) are on a 4-point scale (1 = not at all, 4 = very much so). Typically, respondents are asked to rate statements according to how they generally feel (trait-anxiety scale) and how they feel in the current moment (state-anxiety scale). Total scores range from 20 to 80, with higher scores indicating greater maladjustment.
Time frame: Up to 10 weeks
During the intervention phase the cognitive training group will play games and will need to log the days and duration played.
Time frame: Up to 10 weeks
19-item questionnaire that assesses preference for morning, afternoon, and evening activities. Total score reflects degree of "morningness" or "eveningness" type.
Time frame: Up to 10 weeks
Perceived Stress Scale is a self-report measure of how life situations are perceived as stressful. The scale consists of 15 items corresponding to everyday situation and participants are asked to rate on a scale from 0 (never) to 4 (very often) how often they felt or thought a specific way. Higher scores correspond to higher perceived stress.
Time frame: Up to 10 weeks
Arousal Predisposition Scale is a 12-item inventory that has been designed to measure the degree to which an individual experiences arousal. Higher scores indicate greater predisposition to arousal.
Time frame: Up to 10 weeks
Questionnaire assessing the experience of the game.
Time frame: Up to 10 weeks
21-item inventory that asks respondents to rate on a scale of 0 (no depressive feelings) to 3 (most depressive feelings) their feelings towards various aspects of daily living/situations. Higher total scores indicate worse depressive symptoms.
Time frame: Baseline
10-item questionnaire that assess the frequency of alcohol use and problems associated with alcohol use over the past year.
Time frame: Up to 10 weeks
7- item questionnaire assessing the different kinds of physical activities that the participant does as pat of their everyday life.
Time frame: Baseline
10 question assessment measuring personality
Time frame: Baseline
This questionnaire asks about participants' ability to perform a number of tasks with a computer. Will be examined as a covariate.
University of Missouri-Columbia
Other
Cognitive Training in Mild Cognitive Impairment: Effects on Sleep, Cognition and Arousal
Acronym: TRAIN-MCI
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07363928
Brain Diseases, Central Nervous System Diseases
Cork, Ireland
View Trial DetailsNCT05016960
Cognition Disorders, Cognitive Dysfunction
San Diego, California, United States
View Trial DetailsNCT03682185
Aberrant Motor Behavior in Dementia, Alzheimer Disease
Philadelphia, Pennsylvania, United States
View Trial DetailsNCT04364191
Cognition Disorders, Cognitive Dysfunction
Philadelphia, Pennsylvania, United States
View Trial Details