Cognitive, Emotional and Behavioural Impairments in Patients After Sars-Cov2 Infection

Recent studies suggest cognitive, emotional and behavioural impairments occur in patients after SARS-CoV-2 infection. Problems with memory, attention, information processing and executive functions are particularly prevalent in these patients, probably due to hypothesised sensitivity of the hippocampus to the virus. Cognitive impairment is also present in patients with no neurological, neuropsychological and neuropsychiatric history. Therefore, the aim of the present study is to describe neuropsychological and neuropsychiatric features in patients recovered from moderate to severe forms of Covid-19 some weeks after hospital dismission.

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Key information

Conditions

COVID-19 Coronaviridae Infections Coronavirus Infections Infections Lung Diseases Nidovirales Infections Pneumonia Pneumonia, Viral RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Sars-CoV-2 Infection Virus Diseases

Age range

30 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

"Moriggia Pelascini" Hospital

Gravedona, Como, 22015, Italy

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Positive PCR from nasopharyngeal swab
No ICU admission

Exclusion criteria

Diagnosis of neurologic or psychiatric disorders;
Previous cognitive impairment;
Other medical conditions negatively affecting the cognitive status.

Treatment and study plan

Primary outcomes

Cognitive and neuropsychiatirc symptoms in Covid-19 patients

Time frame: About 20 days after hospital dismission

Prevalence of neuropsychological and neuropsychiatric impairment in patients after hospitalization in patients with Sars-Cov2 infection.

Sponsors and collaborators

Lead sponsor

Ospedale Generale Di Zona Moriggia-Pelascini

Other

Registry information

Official study title

Cognitive and Neuropsychiatric Features of COVID-19 Patients After Hospital Dismission: an Italian Sample.

Important dates

Study start: 2021
Primary completion: 2021
Study completion: 2021
First posted: Dec 3, 2021
Registry last updated: Dec 3, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed