Ghent University
Ghent, Oost-Vlaanderen, 9000, Belgium
NCT Number: NCT02407652
The purpose of this study is to explore the effectiveness of an internet-delivered cognitive control training as a preventive intervention for remitted depressed patients.
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Notify Me23 year–65 year
All sexes
Interventional
Not applicable
Ghent, Oost-Vlaanderen, 9000, Belgium
Prospective studies have linked impaired cognitive control to increased cognitive vulnerability for future depression. Importantly, experimental studies indicate that cognitive control training can be used to reduce rumination and depressive symptomatology in MDD samples. Furthermore, studies exploring the potential of cognitive control training in at-risk undergraduate students indicate that cognitive control training has beneficial effects on rumination, an important vulnerability factor for depression. Provided that remitted depressed patients form a high-risk group for developing future depressive episodes, the current study will explore whether internet-delivered cognitive control training can be used to reduce vulnerability for future depression in remitted depressed patients. The investigators will explore effects on depressive symptomatology, (mal-)adaptive emotion regulation (directly following training and at 3 months follow-up), and indices of functioning (at 3 months follow-up).
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
10 adaptive Paced Auditory Serial Addition Task (PASAT) sessions, 400 trials each
10 low cognitive load sessions, 400 trials each
Time frame: baseline, 2 weeks, 3 months
Assessed using the Ruminative Response Scale (RRS)
Time frame: baseline, 2 weeks, 3 months
Assessed using the Beck Depression Inventory (BDI-II)
Time frame: baseline, 2 weeks, 3 months
Assessed using the Cognitive Emotion Regulation Questionnaire (CERQ)
Time frame: baseline, 3 months
Assessed using the Quality of Life in Depression Scale (QLDS)
Time frame: baseline, 3 months
Assessed using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0)
Time frame: baseline, 3 months
Assessed using the Resilience Scale (RS)
Time frame: baseline, 3 months
Assessed using the Remission of Depression Questionnaire (RDQ)
Time frame: baseline, 2 weeks, 3 months
Assessed using the (non-adaptive) PASAT
Time frame: baseline, 2 weeks, 3 months
Assessed using the Behaviour Rating Inventory of Executive Function Adult Version (BRIEF-A)
University Ghent
Other
Cognitive Control Training as a Preventive Intervention for Depression: A Double-blind Randomized Controlled Trial Study
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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