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Completed

NCT Number: NCT00096642

Cognitive Behavioral Therapy for Early-Onset Depression

Depression is a debilitating illness affecting large numbers of young people. In this study, children and adolescents ages 10 to 17 meeting criteria for clinical depression will participate in a 15-session group therapy (cognitive behavioral therapy or CBT) that teaches strategies for overcoming depressed mood. For half the participants, their parents will also participate in a parent group. By studying the role of parental involvement, we hope to develop more effective treatments for depressed children and teens in the future.

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Key information

Age range

10 year–17 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Centre for Addiction and Mental Health

Toronto, Ontario, M5T 1R8, Canada

About this study

Depression is a debilitating illness affecting large numbers of young people. Psychotherapy approaches have shown some promise in teens, but few studies have examined these interventions when offered in a group format. The role of parents in treatment outcome has also received little attention.

In this study, children and adolescents ages 10 to 17 meeting criteria for clinical depression will participate in a 15-session group therapy (cognitive behavioral therapy or CBT) that teaches strategies for overcoming depressed mood. For half the participants, their parents will also participate in a parent group to help them better manage their depressed children and teens. We will randomly assign children to CBT with or without parental involvement. We hope to show that involving parents results in additional improvements in the children. We will also study factors that predict which children do best in treatment, and maintenance of gains at 6 month and 1 year follow-up. These findings will allow us to provide more effective treatments to depressed children and teens in the future.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children and adolescents meeting DSM-IV criteria for either Major Depression or Dysthymic Disorder.

Exclusion criteria

  • Psychotic,
  • Actively suicidal,
  • IQ less than 80,
  • Unable to speak English

Treatment and study plan

Cognitive behavioral therapy

Behavioral

Cognitive behaviour versus standard care

Primary outcomes

  1. Diagnosis on structured interview

    Time frame: pre and post-intervention

  2. Children's Depression Inventory score

    Time frame: pre- and post-intervention

Secondary outcomes

  1. Multidimensional Anxiety Scale for Children

    Time frame: pre- and post-intervention

  2. Children's Global Assessment Scale

    Time frame: pre- and post-intervention

  3. Brief Family Assessment Measure

    Time frame: pre- and post-intervention

  4. Perceived Competence Scale for Children

    Time frame: pre- and post-intervention

Sponsors and collaborators

Lead sponsor

Centre for Addiction and Mental Health

Other

Registry information

Official study title

Comprehensive Treatment for Depressed Youth: An Outcome Evaluation Study

Important dates

Study start
2002
Primary completion
2006
Study completion
2006
First posted
Nov 15, 2004
Registry last updated
Aug 5, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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