Skip to main content
OpenTrials
Completed

NCT Number: NCT07686510

Coffee Consumption After Laparoscopic Hysterectomy

Postoperative ileus and delayed bowel recovery remain common concerns following laparoscopic hysterectomy despite enhanced recovery protocols. Coffee consumption has been suggested as a simple, safe, and inexpensive intervention that may stimulate gastrointestinal motility and accelerate postoperative recovery. This randomized controlled trial aims to evaluate the effect of postoperative coffee consumption on bowel function recovery and length of hospital stay in women undergoing laparoscopic hysterectomy. Eligible participants are randomly assigned to either a coffee intervention group receiving standard postoperative care plus coffee at predetermined postoperative time points or a control group receiving standard postoperative care alone. The primary objective is to determine whether postoperative coffee consumption improves bowel recovery and shortens hospitalization.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hysterectomy Gastrointestinal Motility Disorder Postoperative Ileus

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Istanbul Bağcılar Training and Research Hospital

Istanbul, 34810, Turkey (Türkiye)

About this study

Laparoscopic hysterectomy is one of the most commonly performed minimally invasive gynecological procedures. Although enhanced recovery after surgery (ERAS) protocols have improved postoperative outcomes, delayed gastrointestinal recovery and postoperative ileus continue to affect patient recovery, comfort, and hospital length of stay.

Coffee contains several bioactive compounds that may stimulate gastrointestinal motility through multiple physiological mechanisms, including increased gastrin secretion, activation of the gastrocolic reflex, and enhanced colonic motor activity. Previous clinical studies have suggested that postoperative coffee consumption may accelerate bowel function recovery after abdominal surgery; however, evidence specific to laparoscopic hysterectomy remains limited.

This single-center, randomized controlled trial evaluates the effectiveness of postoperative coffee consumption in women undergoing laparoscopic hysterectomy. Fifty eligible participants are randomly allocated in a 1:1 ratio to either an intervention group or a control group using block randomization. Participants in the intervention group receive standard postoperative care together with 100 mL of soluble coffee prepared with hot water at postoperative hours 6, 12, and 18, whereas participants in the control group receive standard postoperative care alone.

The study evaluates postoperative bowel recovery by assessing bowel sounds, passage of flatus, passage of stool, abdominal distension, nausea, vomiting, distension-related pain, and length of hospital stay. The findings are expected to provide evidence regarding a simple, low-cost, and feasible nursing intervention that may improve postoperative recovery following laparoscopic hysterectomy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women aged 18 years or older.
  • Scheduled for elective laparoscopic hysterectomy.
  • Able to consume oral fluids according to the ERAS protocol.
  • Able to communicate in Turkish.
  • Willing to participate and provide written informed consent.

Exclusion criteria

  • Emergency surgery.
  • Known allergy or intolerance to coffee or caffeine.
  • Gastrointestinal diseases or conditions affecting bowel motility.
  • Postoperative complications requiring intensive care or preventing oral intake.
  • Withdrawal of informed consent at any stage of the study.

Treatment and study plan

Postoperative Coffee Consumption

Behavioral

Participants received 100 mL of hot soluble coffee prepared with hot water at postoperative hours 6, 12, and 18 in addition to standard postoperative ERAS care.

Primary outcomes

  1. Time to First Passage of Flatus

    Time frame: From the end of surgery until the first passage of flatus, assessed for up to 72 hours after surgery.

    Time from the end of surgery to the first passage of flatus, recorded in hours.

Secondary outcomes

  1. Time to First Defecation

    Time frame: From the end of surgery until the first bowel movement, assessed for up to 72 hours after surgery.

    Time from the end of surgery to the first bowel movement.

  2. Time to First Bowel Sounds

    Time frame: From the end of surgery until the first bowel sounds are detected, assessed for up to 72 hours after surgery.

    Time from the end of surgery to the first audible bowel sounds.

  3. Length of Hospital Stay

    Time frame: From the date of surgery until hospital discharge, assessed for up to 5 days after surgery.

    Duration of hospitalization from surgery until discharge.

Sponsors and collaborators

Lead sponsor

Istanbul Medipol University Hospital

Other

Collaborators

  • Bagcilar Training and Research Hospital

Registry information

Official study title

Effect of Postoperative Coffee Consumption on Bowel Motility and Length of Hospital Stay Following Laparoscopic Hysterectomy: A Randomized Controlled Trial

Acronym: COFFEE-LH

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 7, 2026
Registry last updated
Jul 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.