Coenzyme Q10 and Dentoalveolar Cyst

10 patients in each group will undergo cyst removal under local anesthesia. After cyst removal, the cystic cavity will be filled with placebo gel in the control group or coenzyme gel in the coenzyme group.

Bone density and volume will be assessed by cone beam CT immediately postoperative and 6months later for all patients

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Cyst, Jaw Bone Cysts Cysts Jaw Cysts Jaw Diseases Musculoskeletal Diseases Neoplasms Stomatognathic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Fayoum University

Al Fayyum, 02, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patients with critical-size jaw cysts
Medically stable
No cystic lesion recurrence

Exclusion criteria

Cystic lesion recurrence
Medical problem

Treatment and study plan

Coenzyme Q10

Drug

cystic jaw defect filled with coenzyme Q10 gel

Control group

Drug

cystic jaw defect filled with placebo gel

Primary outcomes

bone density

Time frame: 6 months

measure the bone density of new bone in the cystic cavity at 6 months by cone beam CT

Secondary outcomes

bone volume

Time frame: 6months

measure the bone volume in the defect by cone beam CT at 6 months

Sponsors and collaborators

Lead sponsor

Fayoum University

Other

Registry information

Official study title

The Effect of Coenzyme Q10 on Bone Regeneration in Jaw Defect After Cyst Enculation: A Randomized Controlled Clinical Trial

Important dates

Study start: 2023
Primary completion: 2025
Study completion: 2025
First posted: May 24, 2023
Registry last updated: Mar 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting