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OpenTrials
Completed

NCT Number: NCT00000200

Cocaine Effects in Humans: Physiology and Behavior - 1

The purpose of this study is to compare the effects of buprenorphine or methadone maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving, in opiate-dependent cocaine users.

Completed

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Key information

Conditions

Cocaine-Related Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Columbia University

New York, 10023, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Please contact site for information.

Treatment and study plan

Methadone

Drug

normal maintenance dose

Primary outcomes

  1. Interaction of cocaine and meds on cardio

    Time frame: 3 hr

  2. Interaction of cocaine & meds on coc's subjective

    Time frame: 3 hr

  3. Effects of medication on cocaine craving

    Time frame: 3 hr

Sponsors and collaborators

Lead sponsor

National Institute on Drug Abuse (NIDA)

Nih

Collaborators

  • Columbia University

Registry information

Official study title

Cocaine Effects in Humans: Physiology and Behavior

Important dates

Study start
1997
Primary completion
1998
Study completion
1998
First posted
Sep 21, 1999
Registry last updated
Jan 12, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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