CMR in Myocardial Infarction with Nonobstructive Coronary Arteries

MINOCA is accompanied by a worse prognosis, which is related to the inability to clarify the etiology.CMR has been explicitly recommended by guidelines as an etiologic diagnostic tool for MINOCA. Although CMR-related parameters, such as strain and ECV, have been shown to be associated with prognosis in patients with myocardial infarction. However, the relationship between CMR-strain or ECV and MINOCA is unclear. The aim of this study was to investigate the characterization of CMR-strain or ECV in patients with MINOCA and the relationship with prognosis.

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Key information

Conditions

Cardiac Magnetic Resonance Cardiovascular Diseases Extracellular Volume Heart Diseases Infarction Ischemia MINOCA Myocardial Infarction Myocardial Infarction with Nonobstructive Coronary Arteries Myocardial Ischemia Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Sprains and Strains Strain Vascular Diseases Wounds and Injuries

Sex eligibility

All sexes

Study type

Observational

Primary location

The Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, 221002, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Complete CMR during hospitalization;
CAG results suggesting coronary stenosis of less than 50%;
peak hsTnT above the 99th percentile.

Exclusion criteria

CMR image sequences are missing or of poor quality.

Treatment and study plan

Cardiac MRI

Other

Patients with a diagnosis of MINOCA and completed CMR were included in this study

Primary outcomes

Primary endpoint events included any cause, non-fatal infarction, stroke, or cardiac readmission.

Time frame: All patients were followed until June 30, 2024

Sponsors and collaborators

Lead sponsor

The Affiliated Hospital of Xuzhou Medical University

Other

Registry information

Official study title

Prognostic Value of CMR-related Parameters in Patients with MINOCA

Important dates

Study start: 2019
Primary completion: 2024
Study completion: 2024
First posted: Jul 16, 2024
Registry last updated: Jul 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed