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NCT Number: NCT06444503

Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies

The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies.

This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression and new therapeutic targets.

Recruiting

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Key information

Conditions

Bone Disorder Bone Diseases Musculoskeletal Diseases

Age range

Up to 99 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University Toulouse Hospital

Toulouse, 31000, France

Location status: Recruiting

Location contact

Thomas EDOUARD, MD

CONTACT

[email protected]

0534558555 ext. +33

Thomas EDOUARD, MD

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children (from birth) with growth plate or bone pathology
  • Patients affiliated to or benefiting from a social security scheme
  • Patients able to receive information about the study and to understand the information form in order to participate in the study. This implies :
  • mastery of the French language
  • Not being subject to a restriction of rights by the judicial authorities
  • Patients or legal representatives having given their consent to participate in the study (expression of non-opposition).

Exclusion criteria

  • Patients under legal protection (guardianship, curatorship or safeguard of justice)
  • Pregnant or breast-feeding women

Treatment and study plan

Biological Samples

Other

Blood and urine will be taken in larger quantity

Biological

Other

Surgical residues may be preserved in the event of surgery carried out as part of the treatment.

Primary outcomes

  1. Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologies

    Time frame: Day 0 and through study completion, an average of 5 years

    Blood and urine sampling

Secondary outcomes

  1. Identification of potential markers of disease progression based on new knowledge.

    Time frame: Day 0 and through study completion, an average of 5 years

Study contacts

Contact information is provided by the study sponsor or research team.

Sanaa EDDIRY

CONTACT

[email protected]

0561776110 ext. +33

Thomas EDOUARD, MD

CONTACT

[email protected]

0534558555 ext. +33

Sponsors and collaborators

Lead sponsor

University Hospital, Toulouse

Other

Registry information

Official study title

Creation of a Biological Collection to Study the Pathophysiology and Identify Predictive Factors for the Evolution of Bone, Calcium and Growth Plate Pathologies

Acronym: OSCAR

Important dates

Study start
2024
Primary completion
2034
Study completion
2034
First posted
Jun 5, 2024
Registry last updated
Jun 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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