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Completed

NCT Number: NCT01657279

Clinician JUdgment Versus Risk Score to Predict Stroke outComes: The JURASSIC Clinical Trial

Background: Several risk score models are now available to assist clinicians estimate outcomes after an acute ischemic stroke. Limited information is available on the predictive value of these scores compared to real outcomes and clinical judgment.

Objectives: To compare clinician judgment with the use of a validated stroke risk score (iScore) and patients' outcomes.

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Key information

Conditions

Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disease Cerebrovascular Disorders Ischemic Stroke Nervous System Diseases Vascular Diseases

Age range

20 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

St Michael's Hospital, Toronto, Ontario, Canada

Loading trial locations.

About this study

A convenience sample of 111 practicing clinicians (general and vascular neurologists, internists, and ER physicians) predicted the outcomes of 5 stroke patients based on case summaries. Cases were randomly selected as being representative of the 10 most common clinical scenarios (n=1,415) from a pool of over 12,000 patients admitted to stroke centers in Ontario, Canada. Stroke cases had known clinical presentation, comorbidities, stroke severity, and outcomes.

All participants are active practicing physicians caring for patients with acute stroke. Conditions were standardized to mimic clinical practice.

Main outcomes of interest included 30-day mortality and death or disability at discharge.

Secondary outcome: death or institutionalization at discharge

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Practicing and active physicians managing patients with stroke

Exclusion criteria

  • retired physicians
  • physicians not exposed to care for stroke patients

Treatment and study plan

Clinical scenarios

Other

Clinicians will be randomized to a sequence of 5 clinical scenarios with a variable range of expected outcome [i.e. from low (<10%) to high (>50%) expected risk death at 30 days].

Primary outcomes

  1. 30 Day Mortality or Disability (mRS >3) at discharge

    Time frame: Death after 30 days from ischemic stroke onset or Disability following hospital discharge

Secondary outcomes

  1. Death at 30 days

    Time frame: 30 days

  2. Death or institutionalization at discharge

    Time frame: up to 30 days after discharge

Sponsors and collaborators

Lead sponsor

Unity Health Toronto

Other

Collaborators

  • Heart and Stroke Foundation of Ontario

Registry information

Official study title

Clinician JUdgment Versus Risk Score to Predict Stroke outComes:

Acronym: JURASSIC

Important dates

Study start
2012
Primary completion
2012
Study completion
2012
First posted
Aug 6, 2012
Registry last updated
Oct 30, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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