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NCT Number: NCT03172312

Clinical Utility of Intraoperative Parathyroid Scores System in Thyroidectomy

Ready to establish the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy and study the clinical value of Intraoperative Parathyroid Scores System for thyroidectomy.

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Key information

Conditions

Intraoperative Parathyroid Scores System Endocrine Gland Neoplasms Endocrine System Diseases Head and Neck Neoplasms Hypoparathyroidism Neoplasms Neoplasms by Site Parathyroid Diseases Thyroid Diseases Thyroid Neoplasms

Age range

Up to 60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Wen-xin ZHAO

Fuzhou, Fujian, 350001, China

About this study

IPSS includes transplantation Parathyroid Scores and in situ Parathyroid Scores, the investigators will establish the Intraoperative Parathyroid Scores System by parathyroid size and Blood supply, and recording IPSS, according to certain rules. Parathyroid hormone and calcium were test in d0, d1, d14, d60 post operation. The correlation between Intraoperative Parathyroid Scores and PTH calcium were calculated, and ROC curve and logistic regression were tested for the prediction value.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • postoperative pathology confirmed as thyroid papillary carcinoma;
  • for the first time to undergo thyroid surgery, no history of neck surgery and external radiotherapy;
  • preoperative serum calcium, parathyroid hormone levels were normal;
  • intraoperative and postoperative clinical data integrity, standardized follow-up patients;
  • parathyroid is a tumor violation.

Exclusion criteria

  • serious underlying disease;
  • age greater than 60 years of age or combined with arteriosclerotic disease;
  • patients with postoperative loss;
  • patients with parathyroid disease.

Treatment and study plan

Different range of thyroid surgery

Procedure

Observe and record parathyroid status during thyroid surgery

Primary outcomes

  1. transplantation Parathyroid Scores correlated with transplanted parathyroid function

    Time frame: 2014-2016

    relation with transplantation Parathyroid Scores and transplanted parathyroid hormone

  2. the value of IPSS and in situ Parathyroid Scores

    Time frame: 2014-2016

    relation with Intraoperative Parathyroid Scores and in situ Parathyroid Scores

  3. predicted function of IPSS

    Time frame: 2014-2016

    IPSS and in suit PSS be recoded and D1，D14 PTH Ca2+ were tested

  4. value of IPSS in low PTH patients

    Time frame: 2014-2016

    IPSS and in suit PSS be recoded and D1，D14 PTH Ca2+ were tested

Secondary outcomes

  1. value of IPSS for Surgeon and patient

    Time frame: 2014-2016

    description the clinic value

Sponsors and collaborators

Lead sponsor

Fujian Medical University

Other

Registry information

Acronym: IPSS

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
Jun 1, 2017
Registry last updated
Jun 1, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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