Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats

Further secondary parameters are :

Responders during at day 4 and 5, single symptom scores during 1 to 5 days of observation, pain at begin and end (100mm VAS), assessment of efficacy by physician and patient, consumption of rescue medication

Assessment of safety by physician and patient, frequency of adverse events

Inclusion criteria

• Age > 12 years;
• Acute pharyngitis or tonsillitis with symptoms of throat pain and inflammation of the pharynx and/or tonsils;
• Onset of sore throat less than 72 hours before inclusion ;
• A Tonsillopharyngitis Severity Score ≥6;
• Written informed consent.

Exclusion criteria

• Analgesics <12 hours;
• Antibiotics <24 hours; t
• Topical throat pain medication <4 hours;
• Systemic corticosteroids within the last month;
• Symptoms of primary bacterial pharyngitis or secondary bacterial infection;
• Serious illness such as tumors; allergy to one of the ingredients; pregnancy or lactation;
• Hypersensitivity to ibuprofen;
• Participation in another clinical trial in the previous 30 days.