Clinical Study to Investigate the Effects of a Food Supplement Santa Herba Extract on Weight Loss in Overweight Women

Inclusion criteria

• Subject is able and willing to follow the study protocol procedures to sign the Informed Consent Form prior to screening evaluations
• Overweight and obese women with BMI 25 - 35 kg/m2 (limits included)
• Age: 25 - 60 years
• Subject is in good physical and mental health as established by medical history, physical examination, electrocardiogram, vital signs, results of biochemistry, haematology

Exclusion criteria

• Relevant history or presence of any medical disorder potentially interfering with this study (heavy depression, diabetes, active cancer, severe liver disease, heavy cardiovascular diseases (e.g. stroke, heart attack))
• Chronic intake of medication/dietary supplements with impact on body weight or body composition or lipid modifying products (e.g. protein shakes, statins, omega-3 fatty acids, etc.) 2 months prior to screening or during the study; stable doses of e.g. hypertensive therapy and thyroid gland hormones are acceptable.
• Change in hormonal contraceptive during or at least 3 months before the study
• Consumption of any dietary supplement / fortified food (with exception of vitamin D and mineral supplements e.g. Ca, Mg)
• Low body fat mass measured at screening with BIA ( bioelectrical impedance analysis ) (Cut off-value: <36% body fat).
• Weight loss intervention or recent body weight change > 4.5 kg during last 3 months
• Diet high in vegetables and fruits ≥ 5 portions per day
• Vegan lifestyle
• Smoker > 10 cigarettes / day
• Gastrointestinal diseases/conditions (colitis ulcerosa, Crohn's disease, peptic ulcers, celiac disease)