Sherief Abd-Elsalam
Tanta, 35127, Egypt
Location status: Recruiting
Recruiting
NCT Number: NCT04704947
Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis
Clinical study evaluating selective or nonselective beta blockers use and fracture risk in patients with primary osteoporosis
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
50 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Phase 3
Primary location
About this study
Clinical study evaluating selective or nonselective beta blockers use and if there is fracture risk in patients with primary osteoporosis
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- • Male & female osteoporotic patient aged ≥ 50 years
- Hypertensive & normotensive patients
- BMD T-score ≥ 2.5 or more SD below peak bone mass
Exclusion criteria
- Patients on drugs that may improve osteoporosis disease state such as:
- Angiotensin converting enzyme inhibitor (ACEI) or Angiotensin receptor blockers (ARBs), Thiazide diuretic, Nitrates, Spironolactone, Statins.
Patients on drugs that may worsen osteoporosis disease state such as:
- Corticosteroids, Loop diuretics, Anticonvulsants, Antidepressants, Aromatase inhibitors, Thyroid replacement therapy and Proton pump inhibitors.
Treatment and study plan
nonselective beta blocker
Drugnonselective beta blocker
Other names: Inderal
cardio-selective beta blocker group
Drugcardio-selective beta blocker group
Other names: concor
Alendronate sodium
Drugalendronate sodium
Other names: alendronate
Primary outcomes
-
Number of patients with fracture in each group
Time frame: 1 year
the exact number of patients with fracture in each group
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Sherief Abd-Elsalam
Other
Registry information
Official study title
Clinical Study Evaluating Selective or Nonselective Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis
Important dates
- Study start
- 2017
- Primary completion
- 2030
- Study completion
- 2030
- First posted
- Jan 12, 2021
- Registry last updated
- Jan 12, 2021
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.