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NCT Number: NCT06532214

Clinical Retrospective Study Analysis of Postoperative Complications Following Hepatectomy

Hepatectomy is a crucial surgical method for treating liver diseases such as liver cancer, hepatic hemangiomas, and biliary stones. Although hepatectomy has achieved significant therapeutic effects, postoperative complications remain an inevitable issue. Complications following hepatectomy include liver failure, hepatic vascular thrombosis, wound infection at the hepatic incision, and bile leakage, among others. These complications pose a serious threat to patients' health and life, and also increase the waste of medical resources and the cost of treatment. Currently, research on postoperative complications of hepatectomy mainly focuses on small sample studies from a single center, and most studies only focus on a specific complication, lacking comprehensive and systematic analysis. Therefore, it is necessary to conduct a retrospective study analysis of complications related to hepatectomy to more comprehensively and objectively understand the incidence, risk factors, prevention, and treatment of postoperative complications, providing clinical doctors with more scientific treatment plans and guidance.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Nanfang Hospital

Guangzhou, Guangdong, 510515, China

Location status: Recruiting

Location contact

kai wang

CONTACT

[email protected]

13710574386

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1. Patients aged 18-80 years 2.Patients who underwent liver resection surgery at the participating centers

Exclusion criteria

  • Exclusion criteria are as follows:
  • Prior cancer treatments such as transarterial chemoembolization, ablation, or targeted therapy.
  • Repeat liver resection surgeries.
  • Presence of other malignancies.
  • Concurrent end-stage diseases including active infections, respiratory failure, decompensated heart failure, and autoimmune disease exacerbations.
  • Inadequate clinical data availability in medical records.

Treatment and study plan

International Study Group for Liver Surgery (ISGLS)

Diagnostic Test

According to the ISGLS criteria, the patient was judged to have liver failure and further analysis

Primary outcomes

  1. Post-hepatectomy liver failure (PHLF)

    Time frame: On and after the 5th postoperative day

    PHLF is commonly diagnosed and classified according to the criteria of the International Study Group for Liver Surgery (ISGLS), utilizing markers of liver function measured on or after postoperative day 5 (POD5).

Secondary outcomes

  1. mortality

    Time frame: During 30 days after surgery

    The patient died postoperatively

Study contacts

Contact information is provided by the study sponsor or research team.

Kai Wang

CONTACT

[email protected]

13710574386

Sponsors and collaborators

Lead sponsor

Nanfang Hospital, Southern Medical University

Other

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Aug 1, 2024
Registry last updated
Aug 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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