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Completed

NCT Number: NCT07054151

Clinical Predictors of Capillary Refill Time and Their Association With Triage Categories

This observational study aims to determine the correlation between capillary refill time (CRT) and vital parameters in patients presenting to the emergency department.

It explores whether CRT is associated with triage categories and vital signs in non-traumatic patients, including oxygen saturation (SpO₂), heart rate, systolic and diastolic blood pressure, body temperature, forearm temperature, and respiratory rate.

Patients admitted to the emergency department of a training and research hospital were assigned triage codes (green, yellow, red). Their CRT was measured three times, and vital signs were recorded accordingly.

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Key information

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Buca Training and Research Hospital, Emergency Deaprtment

Izmir, Turkey (Türkiye)

About this study

In the initial evaluation, patients admitted to the emergency department were assigned a triage color code, categorized as green, yellow, or red. In the color-coding system employed, green was designated as low urgency, yellow as medium urgency, and red as urgent. The allocation of triage codes is the responsibility of nurses who have undergone the requisite training. Following the completion of the assigned task, the emergency specialist proceeded to meticulously record a series of physiological parameters. These parameters included the CRT (in seconds), the percentage of oxygen saturation in the blood (SpO2%), the heart rate (in minutes), the systolic and diastolic blood pressure (in mmHg), the body temperature (in degrees Celsius), the forearm temperature measured at the CRT, and the respiratory rate (in minutes). CRT was evaluated three times for each patient, and the mean of these values was recorded as the CRT.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • individuals over the age of 18 years who consented to participate in the study

Exclusion criteria

  • The presence of pregnancy
  • Multiple traumas resulting in hypovolemia
  • The absence of fingers or limbs
  • The utilization of vasopressors or inotropic pharmacological agents
  • The existence of peripheral arterial disease
  • The presence of nail polish or fake nails

Treatment and study plan

No clinical intervention (observational study only)

Other

This is an observational study. No experimental or clinical intervention was applied. Only non-invasive data collection such as capillary refill time and vital sign measurements was performed.

Primary outcomes

  1. Triage Code Assignment

    Time frame: Baseline [within 30 minutes of initial Emergency department admission triage assessment]

    Triage code assignment will be completed within the first 30 minutes of the patient's initial presentation to the emergency department (ED). Patients will be categorized into green, yellow, or red triage groups based on standard emergency triage protocols upon admission.

    Following this, the patient will be transferred to the designated emergency care room (ER) based on the assigned triage code and further clinical evaluation and treatment.

    Initially, the triage nurse will assess the patient and assign the triage code. Following this, the patient will be transferred to the designated emergency care room (ER), where a specialist emergency physician will perform further clinical evaluation and treatment.

  2. Capillary Refill Time (CRT) in Seconds

    Time frame: Single measurement by the emergency physician within 10 minutes of the patient's arrival in the emergency care room

    CRT will be measured in seconds using a stopwatch after pressing the fingertip. The measurement will be repeated three times and average was calculated.Triage code assignment will be completed within the first 30 minutes of the patient's initial presentation to the emergency department (ED). Following this, the patient will be transferred to the designated emergency care room (ER) based on the assigned triage code, and all vital parameters (e.g., capillary refill time, heart rate, blood pressure) will be measured within 10 minutes of entering the emergency care area.

  3. Heart Rate

    Time frame: The patient is then assessed by the emergency physician within 10 minutes of being transferred to the ER triage code section. (Single measurement )

    Heart rate will be recorded using standard clinical devices. Unit: Beats per minute Measurement technique:: Measured using clinical monitor.. Upon the patient's initial presentation to the emergency department (ED), triage code assignment will be completed within the first 30 minutes. Based on the assigned code, the patient will be directed to the appropriate emergency care room (ER). Heart rate measurements will be taken within 10 minutes of the patient's arrival in the emergency care room.

  4. Systolic Blood Pressure

    Time frame: Single simultaneous measurement (systolic and diastolic) by the emergency physician within 10 minutes of arrival in the emergency care room (ER).

    systolic blood pressure will be recorded using standard clinical devices. Unit: mmHg Measurement technique: Measured using clinical monitor.

    Upon the patient's initial presentation to the emergency department (ED), triage code assignment will be completed within the first 30 minutes. Based on the assigned triage code, the patient will be directed to the appropriate emergency care room (ER).

    Systolic blood pressure will be measured once, within 10 minutes of the patient's arrival in the emergency care room.

    Systolic and diastolic blood pressure will be measured simultaneously in a single session within 10 minutes of the patient's arrival in the emergency care room.

  5. Diastolic Blood Pressure

    Time frame: Single simultaneous measurement (systolic and diastolic) by the emergency physician within 10 minutes of arrival in the emergency care room (ER).

    diastolic blood pressure will be recorded using standard clinical devices. Unit: mmHg Measurement technique: Measured using clinical monitor. Upon the patient's initial presentation to the emergency department (ED), triage code assignment will be completed within 30 minutes. Based on the assigned triage code, the patient will be transferred to the appropriate emergency care room (ER).

    Diastolic and systolic blood pressure will be measured simultaneously in a single session within 10 minutes of the patient's arrival in the emergency care room.

  6. SpO2 (Oxygen Saturation)

    Time frame: Single measurement by the emergency physician within 10 minutes of the patient's arrival in the emergency care room

    SpO2 will be recorded using standard clinical devices. Unit: Percent (%) Measurement technique: Measured using pulse oximetry. Oxygen saturation (SpO₂), along with other vital signs (blood pressure, heart rate), will be measured in a single session within 10 minutes of the patient's arrival in the emergency care room.

  7. Respiratory Rate

    Time frame: Following the patient's admission to the ER, the triage nurse determins the patient's triage code. The patient is then assessed by the emergency physician within 10 minutes of being transferred to the ER triage code section. (single timepoint)

    respiratory rate will be recorded using standard clinical devices. Unit: Breaths per minute Measurement technique: Measured using observation and counting.

  8. Forearm Temperature

    Time frame: Single measurement by the emergency physician within 10 minutes of the patient's arrival in the emergency care room (ER).

    Forearm temperature will be recorded using standard clinical devices. Unit: Degrees Celsius Measurement technique: Measured using infrared thermometer.

  9. Body Temperature

    Time frame: Single measurement by the emergency physician within 10 minutes of the patient's arrival in the emergency care room (ER).

    Body temperature will be recorded using standard clinical devices. Unit: Degrees Celsius. Body temperature was measured with a Yobekan model KV-11 infrared measuring device.

    Measurement technique: Measured using infrared thermometer. All vital signs, including body temperature, were assessed sequentially by the same emergency physician within 10 minutes after the patient was transferred to the emergency care room (ER).

Secondary outcomes

  1. Correlation Between Capillary Refill Time and Age

    Time frame: During the study period through data collection and data entry, expected to be completed within an average of 3 months.

    Pearson correlation analysis will be used to assess the correlation between capillary refill time (measured in seconds using a stopwatch and averaged from three measurements) and patient age (recorded in years from patient records).

    Unit of Measure:

    Capillary Refill Time (Mean): seconds Age: years

    Measurement Tool:

    CRT measured with a stopwatch by a trained emergency specialist Age extracted from patient record All CRT measurements will be taken within 10 minutes of the patient's arrival in the emergency care room by the same emergency physician, as part of the initial clinical evaluation.

  2. Association Between Prolonged CRT (>2s) and Triage Category

    Time frame: During the study period through data collection and data entry, expected to be completed within an average of 3 months.

    Logistic regression will be used to assess the association between prolonged CRT (defined as >2 seconds, averaged from three measurements using a stopwatch) and triage category (Green, Yellow, Red) assigned at emergency department admission.

    Unit of Measure:

    CRT: seconds Triage: categorical (Green, Yellow, Red)

    Measurement Tool:

    CRT measured with a stopwatch (three repetitions, averaged) Triage assignment performed by certified triage nurse based on hospital protocol All CRT measurements were performed within 10 minutes of the patient's arrival in the emergency care room by the same emergency physician, as part of the initial vital sign assessment.

Sponsors and collaborators

Lead sponsor

Izmir Democracy University

Other

Registry information

Official study title

Clinical Predictors of Capillary Refill Time and Their Association With Triage Categories From the Emergency Department Perspective: A Cross-Sectional Study

Acronym: CRT_TriageER

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jul 8, 2025
Registry last updated
Jul 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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