Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07554586

Clinical Practices of Extubation After Invasive Mechanical Ventilation

Extubation is a delicate and complex phase of airway management in anesthesia and critical care. A variety of complications are of concern, ranging from transient hypoxemia to the need for reintubation, which can then become life-threatening for the patient.

For this procedure, it may be recommended to use the positive end-expiratory pressure (PEEP) extubation technique to reduce the risks of hypoxemia, atelectasis, and aspiration. However, no specific technique is preferred given the diversity of described procedures (spontaneous ventilation on an auxiliary circuit, PEEP-assisted spontaneous ventilation, adjustment of the APL valve). However, results may vary depending on the patient population (children, adults) and the setting (operating room, intensive care unit).

Given the lack of a preferred technique for performing extubation under positive end-expiratory pressure, the aim of this study is to describe the techniques used by healthcare professionals (physicians, nurse anesthetists, nurses) during the extubation of a surgical or intensive care patient.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU de Nîmes

Nîmes, 30000, France

Location contact

Jean Yves LEFRANT, PHD

CONTACT

[email protected]

+33 4 66 68 30 50

Jordan ALES, MSC

SUB_INVESTIGATOR

Manon LUCHESI, MSC

SUB_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Physicians and students in anesthesiology and critical care,
  • Critical care physicians,
  • State-certified nurse anesthetists (IADE),
  • State-certified nurses (IDE) working in an anesthesia or intensive care team
  • Students (medical or nurse anesthetist) with at least 1 year of extubation experience.

Exclusion criteria

  • Healthcare professionals with no experience in extubation (less than one year of practice) Refusal to participate

Treatment and study plan

Primary outcomes

  1. Extubation technique

    Time frame: baseline

    Frequency of use of the simple suction extubation technique compared to the positive-pressure extubation technique (%)

Study contacts

Contact information is provided by the study sponsor or research team.

Jean Yves LEFRANT, PHD

CONTACT

[email protected]

+33 466 68 30 50

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nīmes

Other

Registry information

Official study title

Clinical Practices of Extubation After Invasive Mechanical Ventilation in Anesthesia and Intensive Care

Acronym: EPP/EPP = 1

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 28, 2026
Registry last updated
May 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.