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NCT Number: NCT01079494

Clinical Pharmacists Role in the Management of Hypertension in Jordan

Background: studies have demonstrated the crucial role of clinical pharmacists as integrated part of heath care team. Not only in Jordan but also in the Middle East region, clinical pharmacy practice is not well established. This current study is the first to evaluate physicians - pharmacists' collaborative approach to uncontrolled blood pressure in Jordan and the Middle East.

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Key information

Conditions

Hypertension Cardiovascular Diseases Vascular Diseases

Age range

21 year–88 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

family medicine clinic JUH

Amman, 13046, Jordan

About this study

Objective: this study aimed to evaluate clinical pharmacists' role in the management of uncontrolled hypertensive patients in Jordan. Design: single blinded randomized controlled clinical trial. Patients: 253 patients with uncontrolled hypertension specified as higher blood pressure readings than the recommended goals by the seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure (JNC VII) at the time of enrollment.

Interventions: patients were randomly allocated to an intervention or control group: 130 and 123 patients, respectively. Patients in both arms were followed up for 6 months. In the intervention group, patients were managed by physician-clinical pharmacist team. In the control group, patients were managed by physician(s) only and were not provided pharmaceutical care services.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with uncontrolled BP, receiving 0-3 antihypertensive drugs with no change in the regimen or dose within the past 3 month.

Exclusion criteria

  • Patients with hypertensive urgency or emergency with BP more than (180/110).
  • Patients with recent stroke or myocardial infraction (within past 6 months).
  • Patients with Class III or IV Chronic heart Failure (CHF).
  • Patients with Unstable angina.
  • Patients with Serious renal or hepatic disease.
  • Pregnant patients.
  • Patients with Dementia or cognitive impairment.
  • If the patient is unable to provide informed written consent.

Treatment and study plan

pharmaceutical care services

Other

Patients treatment related problems and therapeutic needs or complains identified by clinical pharmacist and managed collaboratively by both pharmacist and the physician.

Primary outcomes

  1. percentage of patients who achieved blood pressure goals specified by the JNC VII at each group

    Time frame: 6 month

    defined a goal to be achieved if the systolic blood pressure fell below 140 mm Hg and the diastolic blood pressure fell below 90 mm Hg. Or systolic blood pressure fell below 130 mm Hg and the diastolic blood pressure fell below 80 mm Hg if patient was diabetic.

Secondary outcomes

  1. mean reductions in both systolic and diastolic blood pressure readings

    Time frame: 6 months

    mean reductions in systolic blood pressure (Systolic blood pressure at enrollment - Systolic blood pressure last follow up visit) and diastolic BP (Diastolic blood pressure at enrollment - Diastolic blood pressure last follow up visit) for both study groups

Sponsors and collaborators

Lead sponsor

University of Jordan

Other

Collaborators

  • Jordan Hospital

Registry information

Important dates

Study start
2009
Primary completion
2009
Study completion
2009
First posted
Mar 3, 2010
Registry last updated
Apr 7, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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