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Completed

NCT Number: NCT07434700

Clinical Performance of Lithium Disilicate Veneer-Fixed Dental Prostheses for Incisor Tooth Replacement

This study evaluated a conservative treatment approach for replacing a missing upper front tooth (maxillary incisor). The treatment involved an all-ceramic, resin-bonded fixed dental prosthesis designed as a minimally invasive alternative to conventional bridges.

The prostheses were fabricated from lithium disilicate glass-ceramic and were designed either with a single retainer (bonded to one adjacent tooth) or with two retainers (bonded to two adjacent teeth). All restorations were bonded using light-curing resin cement.

The study assessed the clinical performance of these prostheses over a follow-up period of at least 12 months. Clinical evaluation included assessment of prosthesis integrity and function during the observation period.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

This retrospective case series evaluated the short-term clinical performance of veneer fixed dental prostheses used to replace a missing maxillary incisor. The prostheses were fabricated from lithium disilicate glass-ceramic (IPS e.max Press).

The retainers consisted of labial ceramic veneers bonded to the enamel surfaces of adjacent teeth. Two prosthetic designs were included: a single-retainer (cantilever) design and a two-retainer design. All veneer retainers were cemented using a light-curing resin cement according to standard adhesive clinical procedures.

Existing patient records were reviewed to assess prosthesis survival and clinical success during follow-up visits. Survival was defined as the prosthesis remaining in situ during the observation period. Clinical success was evaluated based on prosthesis integrity, maintenance of function, and absence of technical complications such as fracture or loss of retention. Follow-up duration was at least 12 months after cementation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with a missing maxillary incisor replaced with a veneer fixed dental prosthesis
  • Intact adjacent teeth suitable to serve as abutments
  • Adequate periodontal health and bone support of adjacent teeth
  • Age 18 years or older
  • Minimum of 12 months clinical follow-up available

Exclusion criteria

  • Patients younger than 18 years
  • Adjacent teeth with extensive restorations, structural compromise, or inadequate enamel for bonding
  • Active periodontal disease affecting abutment teeth
  • Presence of parafunctional habits (e.g., bruxism or clenching)
  • Insufficient follow-up (< 12 months)
  • Incomplete clinical records

Treatment and study plan

Lithium disilicate double retainer veneer bridge

Device

Replacing missing maxillary incisor with single retainer lithium disilicate veneer bridge

Lithium disilicate single retainer veneer bridge

Device

Replacing missing maxillary incisor with double retainer lithium disilicate veneer bridge

Primary outcomes

  1. Success rate

    Time frame: 12 months

    The percentage of successful emax veneer briges

  2. Success rate

    Time frame: 12 months

    The percentage of clinically successful bridge after the observation time

Sponsors and collaborators

Lead sponsor

Damascus University

Other

Registry information

Official study title

Lithium Disilicate Veneer-Fixed Dental Prostheses for Anterior Tooth Replacement: Clinical Case Series

Acronym: LiDi-VFDP

Important dates

Study start
2011
Primary completion
2014
Study completion
2014
First posted
Feb 25, 2026
Registry last updated
Feb 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.