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OpenTrials
Completed

NCT Number: NCT03943719

Clinical Impact of the FilmArray Blood Culture Identification Panel Performed on Positive Blood Cultures From Intensive Care Patients With Septicemia

Molecular testing is a largely validated approach allowing rapid identification of positive blood cultures. However, due to its high cost and its limited information on susceptibility, it is considered as an add-on technique reserved for specific patient populations. In our study, we specifically evaluated molecular testing in a critical care setting and measured its impact on the therapeutic management of critically ill with positive blood cultures. Through the analysis of 110 positive blood culture episodes included in both pre- and post intervention period, we measured a drastic 14h-reduction of the time to administration of the optimal antimicrobial treatment with the use of the molecular approach.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Cliniques universitaires St-Luc

Brussels, 1200, Belgium

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult intensive care unit patients with positive blood cultures

Exclusion criteria

  • palliative care patients

Treatment and study plan

FilmArray blood culture identification panel

Diagnostic Test

FilmArray blood culture identification panel is performed 24 hours on 24hours and 7 days a week on positive blood cultures to accelerate pathogens detection

Primary outcomes

  1. Turn Around Time to optimal treatment of septicemia

    Time frame: From positivity detection of positive blood culture to administration of optimal treatment (up to 48 hours)

    Time in minutes

Sponsors and collaborators

Lead sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Other

Collaborators

  • BioMérieux

Registry information

Official study title

The Impact of a Rapid Molecular Identification Test on Positive Blood Cultures From Critically Ill With Bacteremia: a Pre-post Intervention Study

Acronym: SEPSIS2016

Important dates

Study start
2017
Primary completion
2017
Study completion
2018
First posted
May 9, 2019
Registry last updated
May 9, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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