Clinical Features, Outcomes, and Therapeutics of Pregnancy-Related Aortic Dissection

Aortic dissection in pregnancy represents a lethal risk to both the mother and fetus, it has yet to yield the optimal therapeutic strategy. The aim of this study was to characterize the clinical features and outcomes in women with pregnancy-related acute aortic dissection, and to suggest therapeutic guidelines.

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Key information

Conditions

Aortic Dissection Acute Aortic Syndrome Aneurysm Aortic Diseases Cardiovascular Diseases Dissection, Blood Vessel Pregnancy Related Vascular Diseases

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

Beijing Anzhen Hospital, Beijing, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Women who presented with aortic dissection during pregnancy or post partum ≤12 weeks.

Exclusion criteria

Loss of surgical information.

Treatment and study plan

cesarean section and aortic repair

Procedure

The timing of aortic repair and delivery have to be determined based on the type of the dissection, the stage of pregnancy (the gestation age), and the status of the fetus, as well as the level of local neonatal service.

Primary outcomes

30-day mortality

Time frame: 30 days after surgery

Sponsors and collaborators

Lead sponsor

Nanjing Medical University

Other

Collaborators

Beijing Anzhen Hospital
Guangdong Provincial People's Hospital
Shanghai Zhongshan Hospital

Registry information

Official study title

Clinical Features, Outcomes, and Therapeutics of Ppregnancy-related Aortic Dissection

Important dates

Study start: 2022
Primary completion: 2022
Study completion: 2022
First posted: Aug 15, 2022
Registry last updated: Sep 27, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed