Clinical Evaluation of Ceramage Inlays Cemented With Beautilink Self-Adhesive Resin Cement Versus Rely X Resin Cement in Carious Posterior Teeth

Minimally invasive bonded partial restorations have become a crucial component of contemporary dental treatments. They address the shortcomings of direct restorations and provide patients with a less damaging alternative to full coverage restorations, which can be more harmful to the dental structure. Indirect inlay composite restorations have become a popular choice in restorative dentistry due to their aesthetic appeal and durability. These restorations allow for the preservation of tooth structure while utilizing the mechanical advantages of modern adhesive technology, which can reinforce the weakened compromised tooth structure.

The use of different adhesive materials with Ceramage can significantly influence the success of the restoration. Adhesive materials play a crucial role in ensuring a strong bond between the indirect restoration and the tooth structure. Additionally, the choice of adhesive material can also affect the ease of the cementation process. Self-adhesive resin cement simplifies the procedure by eliminating the need for separate bonding agents, thus reducing the risk of technique sensitivity which can lead to more consistent clinical outcomes and improved patient satisfaction.

Overall, the combination of Ceramage with appropriate adhesive materials offers a reliable and aesthetically pleasing solution for indirect inlay composite restorations, enhancing both the biological, functional and esthetic outcomes of dental treatments.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Caries Class II

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cairo University

Cairo, Cairo Governorate, 002, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Posterior vital tooth with a large carious lesion (ICDAS 4/5)
Posterior vital tooth with a broken restoration that should be replaced (ICDAS 4-7/5-7).
Vital, periodontally sound and with positive reaction to cold stimulus.
Fully erupted posterior molar in normal functional occlusion with natural antagonist and adjacent teeth.

Exclusion criteria

Teeth with clinical symptoms of pulpitis such as spontaneous pain or sensitivity to pressure.
Non-vital teeth, Fractured or cracked teeth.
Endodontically treated teeth.
Periodontally affected teeth.

Treatment and study plan

Beautilink SA cement

Other

According to the manufacturer's instructions (BeautiLink SA - Shofu USA)

To enhance the adhesion, adhesive bonding agent BeautiBond Xtreme, Shofu will be applied on the tooth and cured according to the manufacturer's instructions.
Press the plunger of the auto-mix syringe of Beautilink SA to dispence the cement on the adhesive surface of the restoration.
Seat the restoration in the cavity and apply proper pressure after using Teflon to protect the adjacent teeth and help in the removal of the excess material.
Light-cure the excess material for 1-2 sec with a light-curing unit followed by removal of the tack-cured material with a probe.
Using a light-curing unit to cure each surface and marginal areas for 10 seconds. For areas where the light cannot reach, or when using opaque cement, hold the restoration in place for approximately 5 minutes after light-curing to allow for chemical curing.

RelyX resin cement

Other

According to the manufacturer's instructions (Espe).

To enhance the adhesion, adhesive bonding agent 3M™ Scotchbond™ Universal Plus Adhesive will be applied on the tooth and cured according to the manufacturer's instructions.
Application of 3M™RelyX™ Universal Resin Cement into the cavity
Seat the restoration in the cavity and apply proper pressure after using Teflon to protect the adjacent teeth and help in the removal of the excess material.
Light-cure the excess material for 2-3 sec with a light-curing unit followed by removal of the tack-cured material with a probe.
Using a light-curing unit to cure each surface and marginal areas for 10 seconds. For areas where the light cannot reach, or when using opaque cement, hold the restoration in place for approximately 6 minutes after light-curing to allow for chemical curing.

Primary outcomes

Clinical Performance assessing Biological, Mechanical and Esthetic Parameters Using Modified USPHS Criteria

Time frame: T0: 12 months T1: 18 months

Alpha being the best results and Charlie being the worst results

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Eighteen Months Clinical Evaluation of Hybrid Ceramic Inlays Cemented With Giomer Based Self-adhesive Resin Cement Versus Resin-based Cement in Carious Posterior Teeth: Randomized Controlled Clinical Trial

Important dates

Study start: 2025
Primary completion: 2027
Study completion: 2027
First posted: Feb 18, 2025
Registry last updated: Apr 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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