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NCT Number: NCT07239180

Clinical Evaluation Comparing Tunneled Coronally Advanced Flap and Modified Coronally Advanced Tunnel With Connective Tissue Graft for Managing Single Gum Recession

The technique under investigation aims to provide effective root coverage while offering the advantage of being less invasive.

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Key information

Conditions

Single Recession Defects (RT2) Gingival Diseases Gingival Recession Mouth Diseases Periodontal Atrophy Periodontal Diseases Stomatognathic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Limited RCTs have been found in the literature comparing the root coverage capacity of the tunneled coronally advanced flap versus modified coronally advanced tunnel combined with connective tissue graft in single RT2 defects. So, this trial aims to fill this gap of knowledge.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with single RT2 gingival recession defect ≥ 2 mm
  • Age >18 years old.
  • Systemically healthy patients with no contraindications for periodontal surgeries.
  • Gingival and plaque index less than 20%.
  • No previous surgeries at the defect site.
  • Accepts 6 months follow-up period (compliant patients).

Exclusion criteria

  • RT1 gingival recession.
  • Smokers >10 cigarettes a day a contraindicating for any plastic periodontal surgery.
  • Poor oral hygiene.
  • Active periodontitis patients.
  • Patients on medications causing gingival enlargement.
  • Pregnancy.
  • Teeth mobility ≥ 1 mm.
  • Patients using fixed or removable orthodontic appliances.
  • Restoration and/or periapical radiolucency at the defect site.

Treatment and study plan

Modified Coronally Advanced Tunnel with Connective Tissue Graft

Procedure

Modified coronally advanced tunnel with connective tissue graft without vertical releasing incisions

Tunneled Coronally Advance Flap with Connective Tissue Graft

Procedure

Tunneled coronally advance flap with connective tissue graft with one vertical releasing incision

Primary outcomes

  1. Gingival Recession Depth (GRD)

    Time frame: 6 months

    Measuring gingival recession depth (GRD) using UNC Periodontal probe in millimeter (mm)

Secondary outcomes

  1. The Percentage of Mean Root Coverage (MRC %)

    Time frame: 6 months

    Measuring the percentage of mean root coverage (MRC %) using UNC Periodontal Probe in percentage (%)

  2. Complete Root Coverage (CRC)

    Time frame: 6 months

    Measuring the complete root coverage (CRC) visually (Yes/No)

  3. Root Coverage Esthetic Score (RES)

    Time frame: 6 months

    Measuring the root coverage esthetic score (RES) visually with score (0 "minimum" - 10 "maximum")

  4. The Distance between the contact point and the top of the papilla (DCP)

    Time frame: 6 months

    Measuring the distance between the contact point and the top of the papilla (DCP) using UNC periodontal probe in millimeter (mm)

  5. Gingival Recession Width (RW)

    Time frame: 6 months

    Measuring the gingival recession width (RW) using UNC periodontal probe in Millimeter (mm)

  6. Probing Pocket Depth (PPD)

    Time frame: 6 months

    Measuring the probing pocket depth (PPD) using UNC periodontal probe in Millimeter (mm)

  7. Clinical Attachment Level (CAL)

    Time frame: 6 months

    Measuring the clinical attachment level (CAL) using UNC periodontal probe in Millimeter (mm)

  8. Gingival Index (GI)

    Time frame: 6 months

    Measuring the gingival index (GI) using UNC periodontal probe with score (0 "minimum" - 3 "maximum")

  9. Plaque Index (PI)

    Time frame: 6 months

    Measuring the plaque index (PI) using UNC periodontal probe with score (0 "minimum" - 3 "maximum")

  10. Keratinized Tissue Width (KTW)

    Time frame: 6 months

    Measuring the keratinized tissue width (KTW) using UNC periodontal probe in Millimeter (mm)

  11. Gingival Thickness (GT)

    Time frame: 6 months

    Measuring the gingival thickness (GT) using endodontic file in Millimeter (mm)

  12. Postoperative Patient Satisfaction (Visual Analogue Scale)

    Time frame: 6 months

    Measuring the postoperative patient satisfaction (Visual Analogue Scale) using Patient's questionnaire with score (0 "minimum" -10 "maximum")

Study contacts

Contact information is provided by the study sponsor or research team.

Khaled Hashem Kamal, Masters Degree

CONTACT

[email protected]

00201281033350

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Clinical Evaluation of Tunneled Coronally Advance Flap (TCAF) Versus Modified Coronally Advanced Tunnel With Connective Tissue Graft in Management of Single Recession Defects (RT2): A Randomized Clinical Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 20, 2025
Registry last updated
Nov 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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