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NCT Number: NCT04481087

Clinical Comparison of Different Adhesives in NCCLs

The aim of this randomized, controlled, prospective clinical trial is to evaluate the performances of a universal adhesive in three different application modes, a self-etch adhesive and an etch&rinse adhesive in restoration of non-caries cervical lesions. Thirty-four patients will receive restorations. Lesions will be divided into 5 groups according to adhesive systems and application modes: CU-SE: Clearfil Universal Bond Quick in self-etch mode, CU-SLE: Clearfil Universal Bond Quick in selective etch mode, CU-ER: Clearfil Universal Bond Quick in etch&rinse mode, CSE: Clearfil SE Bond, TB: Tetric N-Bond. Restorations (Tetric N-Ceram composite) will be scored with regard to retention, marginal discoloration, marginal adaptation, recurrent caries and post operative sensitivity using modified USPHS criteria after 48 months. Two examiners who is not involved in the placement of restorations will conduct the evaluations. Descriptive statistics will be performed using Chi-square tests.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hacettepe University

Ankara, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • being 18 years or older,
  • having no medical or behavioral problems preventing then from attending review visits,
  • having at least 5 tooth with NCCLs
  • having antagonist teeth

Exclusion criteria

  • poor gingival health,
  • uncontrolled, rampant caries,
  • bruxism,
  • removable partial dentures,
  • xerostomia

Treatment and study plan

Clearfil Universal Bond Quick

Device

Adhesive systems

Clearfil SE Bond

Device

Adhesive systems

Tetric N-Bond

Device

Adhesive systems

Primary outcomes

  1. Clinical performances of different adhesives

    Time frame: two years

    Two year examinations according to USPHS criteria

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Important dates

Study start
2018
Primary completion
2018
Study completion
2026
First posted
Jul 22, 2020
Registry last updated
Sep 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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