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NCT Number: NCT04186078

Clinical Characteristics of Patients With Sleep Apnea in Korea

Sleep-disordered breathing including obstructive sleep apnea (OSA) is an extremely common medical disorder associated with important morbidity. The purpose of this study is to understand the clinical features and course of patients with sleep apnea in Korea. Participants who are suspected of sleep apnea due to symptoms such as snoring, witnessed apneas, waking up with a choking sensation, excessive sleepiness, non-restorative sleep, difficulty initiating or maintaining sleep, fatigue or tiredness, and morning headache will be prospectively recruited at the outpatient clinic of Seoul National University Hospital. After polysomnography (PSG) or respiratory polygraphy, patients with sleep apnea including OSA and central sleep apnea (CSA) will be followed regularly. Participants not having sleep apnea (apnea-hypopnea index < 5/hour) will only have a baseline visit. For only participants with the informed consent of donating blood, their blood samples will be collected and stored in the Seoul National University Hospital-Human Biobank (SNUH-HUB).

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Key information

Age range

19 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Seoul National University Hospital

Seoul, 03080, South Korea

Location status: Recruiting

Location contact

Jaeyoung Cho, MD

CONTACT

[email protected]

82-2-2072-2503

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants who are suspected of sleep apnea due to symptoms such as snoring, witnessed apneas, waking up with a choking sensation, excessive sleepiness, non-restorative sleep, difficulty initiating or maintaining sleep, fatigue or tiredness, and morning headache

Exclusion criteria

  • None

Treatment and study plan

Primary outcomes

  1. The number of participants with adherence to positive airway pressure (PAP) therapy

    Time frame: Median follow up of 2 years

    PAP adherence is defined as the use of PAP therapy for ≥4 h/night on ≥70% of nights

Secondary outcomes

  1. The number of deaths

    Time frame: Median follow up of 15 years

    The number of deaths

  2. The cause of death

    Time frame: Median follow up of 15 years

    The cause of death

Other outcomes

  1. Change of FEV1 and FVC in patients with OSA

    Time frame: Median follow up of 5 years

    Change of forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) in patients with OSA

Study contacts

Contact information is provided by the study sponsor or research team.

Jaeyoung Cho, M.D.

CONTACT

[email protected]

+82-2-2072-2503

Sponsors and collaborators

Lead sponsor

Seoul National University Hospital

Other

Registry information

Official study title

Clinical Characteristics of Patients With Sleep Apnea in Korea: a Prospective Cohort Study

Important dates

Study start
2019
Primary completion
2045
Study completion
2046
First posted
Dec 4, 2019
Registry last updated
Apr 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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