Clinical Characteristics and Prognosis of Acute Stroke in Pregnancy and Puerperium

• Case-control Study and Cohort Study on Recurrent Stroke Risk:

Inclusion criteria

• Female patients ≥18 years of age;
• Patients or their legally acceptable representatives or relatives agree to collect personal information for this study and sign an oral or online written informed consent.

Exclusion criteria

• Patients or their legally acceptable representatives or relatives refuse follow-up;
• Patients missing critical baseline demographic, clinical or neuroimaging data.

• Cohort Study on Offspring Outcomes:

Inclusion criteria

• Female patients ≥18 years of age;
• Patients in pregnancy or within 6 weeks postpartum;
• Patients or their legally acceptable representatives or relatives agree to collect personal information for this study and sign an oral or online written informed consent.

Exclusion criteria

• Patients or their legally acceptable representatives or relatives refuse follow-up;
• Patients missing critical baseline demographic, clinical or neuroimaging data;
• Patients whose offsprings have congenital malformation or inborn error of metabolism;
• Patients with complications which may affect cerebral blood flow supply, such as amniotic fluid embolism, in pregnancy;
• Patients whose family members other than the parents and siblings of their offsprings have a history of severe mental illness, such as mental retardation, autism and schizophrenia;
• Patients undergo acute myocardial infarction in pregnancy;
• Patients undergo non-spontaneous stroke events due to other causes, such as cerebral infarction or hemorrhage caused by surgery.