Lotrafilcon B contact lenses with added wetting agent
DeviceSilicone hydrogel contact lenses
Other names: AIR OPTIX® plus HYDRAGLYDE® (AOHG)
NCT Number: NCT03026257
The purpose of this study is to evaluate worn AIR OPTIX® plus HYDRAGLYDE® (AOHG) lenses cleaned and disinfected with HYDRAGLYDE® containing lens solutions compared to each of the control habitual silicone hydrogel (SiHy) lenses cleaned and disinfected with habitual multi-purpose solution (MPS) for cholesterol uptake.
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Alcon Investigative Site, Waterloo, Ontario, Canada
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Silicone hydrogel contact lenses
Other names: AIR OPTIX® plus HYDRAGLYDE® (AOHG)
Habitual silicone hydrogel contact lenses
Other names: Bausch + Lomb ULTRA™ (Ultra)
Multi-purpose disinfecting solution for contact lens care
Other names: OPTI-FREE® PureMoist® (OFPM)
Solution for contact lens cleaning and disinfecting
Other names: CLEAR CARE® PLUS/AOSEPT® PLUS with HYDRAGLYDE® (CCP)
Habitual silicone hydrogel contact lenses
Other names: Johnson & Johnson ACUVUE® VITA™ (Vita)
Habitual silicone hydrogel contact lenses with a replacement pair issued after 2 weeks
Other names: Johnson & Johnson ACUVUE® OASYS® 2- Week with HYDRACLEAR® PLUS (Oasys)
Habitual silicone hydrogel contact lenses
Other names: CooperVision® Biofinity® (Biofinity)
Multi-purpose solution for contact lens care according to participant's habitual brand, used per manufacturer's instructions
Time frame: Day 30
The contact lens worn in the right eye was removed and stored dry and frozen until analysis. Total cholesterol uptake (cholesterol and cholesterol esters) was evaluated from a sample of the right contact lenses from each site and measured in micrograms. Lower total cholesterol uptake indicates increased lens performance.
Alcon, a Novartis Company
Industry
Clinical Assessment of a Regimen of AIR OPTIX® Plus HYDRAGLYDE® Silicone Hydrogel Lenses and HYDRAGLYDE® Containing Lens Care Solutions
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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