Clinical Aspects of Patients With Benign Paroxysmal Positional Vertigo (BPPV) and Migraine

The aim of this study is to analyze the clinical aspects of patients with BPPV associated with migraine. It is our purpose to clarify weather migraine is a risk factor for BPPV if the clinical aspect and the therapeutic outcome is different.

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Key information

Conditions

Migraine Benign Paroxysmal Positional Vertigo Brain Diseases Central Nervous System Diseases Ear Diseases Headache Disorders Headache Disorders, Primary Labyrinth Diseases Migraine Disorders Nervous System Diseases Neurologic Manifestations Otorhinolaryngologic Diseases Pathological Conditions, Signs and Symptoms Positional Vertigo Signs and Symptoms Vertigo Vestibular Diseases

Age range

10 year–84 year

Sex eligibility

All sexes

Study type

Observational

About this study

Two hundred and sixty-three patients with BPPV were enrolled in this retrospective study. All patients' charts were reviewed by independent observer. The type of BPPV and associated problems were noted. Patients with migraine were investigated in terms of age, gender, symptoms, affected side and the cure rate. Their data were compared with those having no migraine. Mean values and standard deviations (± SD) were calculated. One way ANOVA test was used for the analysis. Significance was set at p < 0.005.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients who had history of head-induced positional and brief vertigo and who have been confirmed by VNG were included

Exclusion criteria

Patients with balance problem other than BPPV,
Patients receiving any medication prior to therapeutic maneuver were excluded

Treatment and study plan

Particle re-positioning maneuver

Procedure

Patients with posterior canal BPPV (PC-BPPV) were treated with Epley maneuver. Patients with superior canal (SC-BPPV) were treated with Li or reverse Epley maneuver. Patients with lateral canal (LC) apogeotropic or geotropic nystagmus were treated with Barbeque, Semont's or Gufoni maneuvers. If geotropic or ageotropic type nystagmus is equal intensity on both sides. The involved side was determined according to the patient sense of disturbance or lying down positioning test. If the patient has involvement of both sides according to Dix-Hallpike maneuver. Therapeutic maneuver was applied to the more severe side. All patients were re-evaluated at maximum 7 days.

Primary outcomes

Number of patients who had normal vestibular response to provocative tests 7 days after re-positioning maneuver

Time frame: 7 days

Every patient with BPPV who had positional nystagmus during Dix-Hallpike and head-roll provocative maneuvers will be treated with Epley or barbeque particle re-positioning maneuvers. Balance (positional nystagmus) of patients 7 days after re-positioning maneuvers will be assessed.

Sponsors and collaborators

Lead sponsor

Anadolu Medical Center

Other

Registry information

Important dates

Study start: 2015
Primary completion: 2015
Study completion: 2015
First posted: Nov 26, 2015
Registry last updated: Nov 26, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed