Clinical and Therapeutic Characteristics of Geriatric Patients Hospitalized for Heart Failure (AGING HF Study (AGe and Heart Failure IN Geriatrics))

This retrospective (between April 2020 and December 2023) then prospective (between January 2024 and August 2026), non-interventional cohort study has as its main objective to evaluate the clinical and therapeutic characteristics of patients aged 75 and over hospitalized in geriatrics for heart failure and also to evaluate the clinical characteristics and triggering factor(s) of acute heart failure.

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Key information

Conditions

Patients Hospitalized in Geriatrics for Heart Failure Cardiovascular Diseases Heart Diseases Heart Failure Patients Aged 75 and Over

Age range

75 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

Multicenter study, including patients aged 75 and over, hospitalized in geriatrics and having suffered heart failure in the geriatric wards of 3 centers. The following elements will be collected:

Demographic data
History (comorbidities)
Type of heart disease
Frailty criteria
Clinical signs of heart failure
Geriatric syndromes (falls, cognitive disorders, (MMSE) confusion, malnutrition, loss of autonomy (ADL, IADL), bedsores)
Biology available (CBC, ionogram, creatinine, NT pro BNP, BHC, troponin, TSH, HBA1C)
ECG and echocardiography data
Treatment on admission, during stay and on discharge
Mode of discharge and length of stay
Follow-up at 3, 6, 9 months and one year, through telephone calls with the patient, caregiver or attending physician. Questions will cover various aspects of health and quality of life, physical activity limitations, autonomy, symptoms, anxiety, depression, as well as neurocognitive status (using adapted questions).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients aged 75 and over Hospitalized in a geriatric ward with heart failure No oral opposition from patient

Exclusion criteria

Patient under 75 years of age Patient not wishing to participate in the study Subject under guardianship/curatorship/supervision of justice

Treatment and study plan

Primary outcomes

Evaluate the clinical and therapeutic characteristics of elderly patients hospitalized in geriatrics for heart failure

Time frame: 36 months

To Evaluate the clinical and therapeutic characteristics of elderly patients hospitalized in geriatrics for heart failure with 80% power and 5% alpha risk and expressed as a percentage.

Secondary outcomes

Factors associated with patients hospitalization or rehospitalization

Time frame: 12 months

Quantitative data will be described as mean ± standard deviation. Qualitative variables will be expressed as percentages Statistical differences (hospitalized and/or deceased vs. non-rehospitalized and/or non-deceased patients) will be assessed using the Mann-Whitney U-test and Student's t-test for non-parametric and parametric continuous variables, respectively. Discrete variables will be normally distributed, and by the Mann-Whitney test for those not normally distributed. Survival curves will be drawn to analyze mortality and hospitalizations. Evaluated using the χ2 or Fisher test. Differences between groups will be assessed by ANOVA for the variables

Study contacts

Contact information is provided by the study sponsor or research team.

Isabelle DUFOUR

CONTACT

[email protected]

+33 (01) 185 78 10 10

Prisca LUCAS, Project manager

CONTACT

[email protected]

+ 33 (01)85 78 10 10

Sponsors and collaborators

Lead sponsor

Gérond'if

Other

Registry information

Official study title

Clinical and Therapeutic Characteristics of Geriatric Patients Hospitalized for Heart Failure

Acronym: AGING HF

Important dates

Study start: 2024
Primary completion: 2027
Study completion: 2028
First posted: Apr 22, 2024
Registry last updated: Apr 22, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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