Clinical and Prognostic Significance of Periodontitis in Patients With Arterial Hypertension

As part of a prospective study, to evaluate the effect of periodontitis on the course of hypertension at baseline, during 6 and 12 months

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Arterial Hypertension Cardiovascular Diseases Hypertension Inflammation Mouth Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Periodontal Diseases Periodontitis Stomatognathic Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University hospital #1

Moscow, Russia

About this study

The study focuses on following tasks: to evaluate and compare arterial stiffness in patients with hypertension and the control group, the effect of treatment and control of clinical manifestations of periodontitis in patients with hypertension and the control group, the effect of treatment and control of clinical manifestations of periodontitis on the level of CRP in patients with hypertension and the control group, the effect of periodontitis control on the dynamics of OH, LDL, TG, uric acid, and fasting glycemia levels, the effect of periodontitis on the risk of atrial fibrillation/flutter in patients with arterial hypertension, to develop an information platform for patients with periodontitis for early detection of CVD risks and control of modifiable risk factors

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age (18 years and older)
Written informed consent signed

Exclusion criteria

Failure to follow up

Treatment and study plan

Orthopantomography

Diagnostic Test

Orthopantomography

Primary outcomes

Triglyceride level

Time frame: 12 months from inclusion

Triglyceride level
Low density lipoprotein level

Time frame: 12 months from inclusion

Low density lipoprotein level

Sponsors and collaborators

Lead sponsor

I.M. Sechenov First Moscow State Medical University

Other

Registry information

Important dates

Study start: 2023
Primary completion: 2025
Study completion: 2026
First posted: May 18, 2026
Registry last updated: May 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed