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OpenTrials
Completed

NCT Number: NCT02373345

Clinical and Neuromechanical Predictors for the Evolution of Chronic Non-specific Low Back Pain

The purpose of the present study is to determine the association between factors known to be associated with the development of chronic low back pain (psychological and biological) and the evolution of functional disability in individuals with a history of low back pain. To do so, 100 individuals with a history of nonspecific low back pain will be followed over a period of 18 months. During this time frame, participants will be evaluated three times in the laboratory (initial, at 6 months and at 18 months) to determine pain and tolerance thresholds, pain inhibition processes as well as neuromuscular activation. Moreover, these participants will be assessed every three months (initial, 3, 6, 9 12, 15 and 18 months) for functional disability and pain intensity levels of their low back pain as well as for psychological symptoms usually associated with the development of chronic low back pain. It is hypothesized that high psychological symptoms measured initially will be associated with high functional disability throughout the study .

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Key information

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Université du Québec à Trois-Rivières

Trois-Rivières, Quebec, G9A 5H7, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • To have experienced at least one episode of disabling (resulting in loss of work or modified tasks at work) nonspecific low back pain in the past three years.

Exclusion criteria

  • Specific causes of low back pain, arthritic conditions, other chronic pain conditions

Treatment and study plan

Primary outcomes

  1. Change from baseline in disability (Roland-Morris Disability Questionnaire)

    Time frame: baseline, 3 months, 6, months. 9 months, 12 months, 15 months, 18 months

    Roland-Morris Disability Questionnaire

Sponsors and collaborators

Lead sponsor

Université du Québec à Trois-Rivières

Other

Collaborators

  • Chaire de recherche en chiropratique FRCQ
  • Institut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail

Registry information

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Feb 27, 2015
Registry last updated
May 17, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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