Clinical and Laboratory Study of Lysozyme Deposition on Daily Disposable Contact Lenses

Inclusion criteria

• The subject must read, understand, and sign the Statement of Informed Consent and receive a fully executed copy of the form.
• The subject must appear able and willing to adhere to the instructions set forth in the clinical protocol.
• The subject must be willing to follow instructions and maintain the appointment schedule.
• The subject must be between 18 and 40 years of age (inclusive).
• The subject's vertex corrected spherical equivalent distance refraction must be in the range of -0.50D to -6.00D in each eye (inclusive).
• The subject's refractive cylinder must not exceed -1.25DC in each eye after vertexing to the corneal plane.
• The subject must be a current wearer of spherical, soft contact lenses (no toric, bifocal or multifocal contact lenses, no extended wear or monovision) for at least 5 days/week and at least 8 hours/day during to month prior to enrollment.
• The subject must own a wearable pair of spectacles and wear them the day of the initial visit.
• The subject must be an existing wearer of spherical soft contact lenses in both eyes.
• The subject must have normal eye (i.e., no ocular medications or infections of any type).
• The subject must be able to wear the study lenses for a minimum seven hours per day.

Exclusion criteria

• Any ocular or systemic allergies or diseases that may interfere with contact lens wear (at the investigator's discretion).
• Any systemic disease, autoimmune disease, or use of medication, which may interfere with contact lens wear (at the investigator's discretion).
• Currently pregnant or lactating (subjects who become pregnant during the study will be discontinued).
• Any infectious disease (e.g., hepatitis, tuberculosis) or a contagious immunosuppressive disease.
• Any active ocular infection.
• Is using any topical medication including artificial tears (ATS) up to two weeks prior to the screening visit.
• Any participants whose habitual contact lenses are used as an extended wear regimen.
• Entropion, ectropion, extrusions, chalazia, recurrent styes, glaucoma, history of recurrent corneal erosions, aphakia, or moderate or above corneal distortion by keratometry.
• Clinically significant (grade 3 or 4) corneal edema, corneal vascularization, corneal staining, or any other abnormalities of the cornea which would contraindicate contact lens wear; clinically significant (grade 3 or 4) tarsal abnormalities or bulbar injection which might interfere with contact lens wear.
• Any know hypersensitivity or allergic reaction to study products.
• Participation in any contact lens or lens care product clinical trial within seven days prior to study enrollment.
• Employee or family member of the Center for Contact Lens Research (e.g., Investigator, Coordinator, Technician).