Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions

Inclusion criteria

• The subject must read, understand, and sign the STATEMENT OF INFORMED CONSENT and receive a fully executed copy of the form.
• The subject must appear able and willing to adhere to the instruction set forth in this clinical protocol.
• The subject must be between 18 and 69 years of age.
• The subject must be willing to participate in a 9-month study.
• The subject must require a visual correction in both eyes.
• Subjective refraction must result in a vertex-corrected spherical contact lens prescription of +2.00D to -8.00D in each eye.
• The subject must have best-corrected visual acuity of 0.20 or better in each eye.
• The subject must be a current wearer of spherical soft contact lenses (no bifocal contact lenses or monovision) for at least 5 days/week and at least 8 hours/day during the month prior to enrollment.
• The subject must require no more than -1.25D cylindrical correction in each eye after vertexing to the corneal plane.
• The subject must have normal eye with no evidence of abnormality or disease that in the opinion of the investigator would contraindicate contact lens wear.

Exclusion criteria

• Self-reported current pregnancy or lactation or plans to become pregnant during the study period (subjects who report becoming pregnant during the study will be discontinued).
• Self-reported adverse reaction to a contact lens solution to be used in the study that in the opinion of the investigator would contraindicate use of that solution.
• Any previous ocular or intraocular surgery (e.g. radial keratotomy, PRK, LASIK, etc.).
• Any clinically meaningful slit lamp findings contraindicating contact lens wear (e.g. equal to or greater than Grade 3 finding of edema, corneal neovascularization, corneal staining, tarsal abnormalities, conjunctival injection, blepharitis/meibomian gland dysfunction) on the study specific classification scale or any other ocular abnormality that in the opinion of the investigator would contraindicate contact lens wear.
• Any active ocular infection.
• Current use of topical ophthalmic medications.
• History of binocular vision abnormality or strabismus.
• More than occasional use of dry eye/rewetting drops (more than 2 times per day on average).
• Any infectious disease (e.g. hepatitis, tuberculosis) or a contagious immunosuppressive disease (e.g. HIV) by self-report.
• History of severe allergic reaction or anaphylaxis.
• Other active ocular disease that in the opinion of the investigator would contraindicate contact lens wear.
• Employee of the investigational clinic (e.g. investigator, coordinator, technician)
• They have taken part in any other clinical trial or research, within two weeks prior to starting this study.