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OpenTrials
Recruiting

NCT Number: NCT05480644

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

The purpose of this protocol is to create a repository of blood samples from patients diagnosed with primary and metastatic brain tumors who are being seen in the Department of Radiation Oncology at Duke Cancer Center.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Duke Cancer Center

Durham, North Carolina, 27710, United States

Location status: Recruiting

Location contact

Eugene Vaios, MD MBA

PRINCIPAL_INVESTIGATOR

Kaitlin Bailey, RN

CONTACT

[email protected]

919-668-3726

Linda Kaltenbach, PhD

CONTACT

[email protected]

Scott Flody, MD PhD

PRINCIPAL_INVESTIGATOR

Zach Reitman, MD PhD

PRINCIPAL_INVESTIGATOR

About this study

Repository blood samples will be used to study the association of circulating biomarkers with radiation therapy outcomes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Have a confirmed diagnosis of primary or metastatic brain tumor (histology or imaging as appropriate)

Exclusion criteria

  • None

Treatment and study plan

Primary outcomes

  1. Number of circulating immune cells in peripheral blood

    Time frame: 6 weeks post radiation therapy

    reported as mean +/- standard deviation

Study contacts

Contact information is provided by the study sponsor or research team.

Kaitlin Bailey, RN OCN

CONTACT

[email protected]

(919) 668-3726

Linda Kaltenbach, PhD

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Duke University

Other

Registry information

Important dates

Study start
2022
Primary completion
2032
Study completion
2032
First posted
Jul 29, 2022
Registry last updated
Nov 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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