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Completed

NCT Number: NCT01311193

Circadian Sleep-wake Cycles and Light Therapy in Borderline Personality Disorder

Individuals with borderline personality disorder (BPD) frequently suffer from emotional instability, daytime fatigue and sleep disturbances. The investigators examined circadian rhythms, sleep and well-being in women with BPD under their habitual life conditions with and without light treatment.

Treated women diagnosed with BPD were investigated during 3 weeks without and 3 weeks with morning LT. Rest-activity cycles were continuously measured using wrist actigraphy, together with proximal skin temperature. Saliva samples were collected weekly to determine the diurnal melatonin rhythm. A range of self-ratings and questionnaires were used to assess depression and clinical state throughout the 6-week protocol. Ten matched healthy women followed the same 6-week protocol without light treatment.

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Key information

Conditions

Borderline Personality Disorder Behavior Behavioral Symptoms Depression Mental Disorders Nervous System Diseases Parasomnias Personality Disorders Sleep Disturbances Sleep Wake Disorders

Age range

20 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Centre for Chronobiology, Psychiatric Hospital, University of Basel

Basel, Canton of Basel-City, 4012, Switzerland

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Borderline Personality Disorder (DSM IV-criteria)
  • German-speaking
  • normal ocular function

Exclusion criteria

  • lack of compliance

Treatment and study plan

light therapy

Other

early morning exposures to bright light, 8000lux for 40min, daily during 3 weeks

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Collaborators

  • Lumie UK
  • Velux Fonden

Registry information

Official study title

Circadian Sleep-wake Cycles, Well-being and Light Therapy in Borderline Personality Disorder

Important dates

First posted
Mar 9, 2011
Registry last updated
Mar 9, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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