Circadian Rhythm and Attack-timing in Episodic Cluster Headache Patients in- and Outside of Bout: an Actigraphic Study

The aim is to investigate circadian rhythm in episodic cluster headache patients in- and outside of bout. This will be done using actigraphy and a short diary for 2 weeks in each period. A secondary outcome is to look at attack occurence and physical activity before and during an attack.

PATIENTS

Inclusion criteria

• Age between 18 and 65 years of age
• Episodic cluster headache
• The patient can differentiate cluster headache from other primary headaches if he suffers from any.

Exclusion criteria

• Circumstances, determined by the PI, that makes the patient ineligible.
• Changes in preventive medication within 7 days before the study initiation and during the 2 weeks.
• Changes in antidepressive medication or antipsychotic medication within 2 weeks before the study initiation and during the 2 weeks.
• Serious somatic and/or psychiatric disorders
• Alcohol intake > 50 units pr.week
• Pregnancy / breastfeeding
• Patient cannot accept the conditions of the trial
• Patient does not understand Danish.

CONTROLS

Inclusion criteria

• Age between 18 and 65 years of age

Exclusion criteria

• Circumstances, determined by the PI, that makes the patient ineligible.
• Any primary headache more than 1 day / month
• Diagnosed with a secondary headache
• Treatment with antidepressive medication or antipsychotic medication within 2 weeks before the study initiation and during the 2 weeks.
• Serious somatic and/or psychiatric disorders
• Alcohol intake > 14 / 7 units pr.week (males / females)
• Pregnancy / breastfeeding
• Patient cannot accept the conditions of the trial
• Patient does not understand Danish.