Recruiting

NCT Number: NCT06927011

Chronic Loose Stools Following Right-sided Hemicolectomy for Colon Cancer and the Association With Bile Acid Malabsorption and Small Intestinal Bacterial Overgrowth Using a Novel Sampling Device

The goal of this clinical research study is to learn about gastrointestinal symptoms in participants who have undergone SC or RC and their impact on the quality of life of these participants.

Recruiting

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Key information

Conditions

Colon Cancer Colonic Diseases Colonic Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site

Age range

20 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

MD Anderson Cancer Center

Houston, Texas, 77030, United States

Location status: Recruiting

Location contact

Anusha Thomas, MBBS

CONTACT

[email protected]

713-794-1439

Anusha Thomas, MBBS

PRINCIPAL_INVESTIGATOR

About this study

To estimate the microbiota and bile acid profiles at multiple levels of the small intestine and proximal neo-colon in patients after RC and participants after SC.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Both men and women of all races and ethnic groups are eligible for this trial who meet the above criteria.

Exclusion criteria

Children will not be enrolled in this study.
Pregnant women will not be enrolled in this study.
Cognitively impaired subjects will not be enrolled in this study.

Treatment and study plan

Capscan

Behavioral

Participants will be asked to swallow 2 small devices (called Capscan), which will collect samples of intestinal fluid as they move through participants small intestine and colon. This device is not FDA approved but has been deemed to have no significant risk. The investigator can explain how it is designed to work. Participants will also answer surveys about participants quality of life.

Participants in this study will be over after all study procedures are completed.

Primary outcomes

Overall Survival (OS)

Time frame: Through study completion; an average of 1 year.

Study contacts

Contact information is provided by the study sponsor or research team.

Anusha Thomas, MBBS

CONTACT

[email protected]

(713) 794-1439

Sponsors and collaborators

Lead sponsor

M.D. Anderson Cancer Center

Other

Registry information

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2028
First posted: Apr 15, 2025
Registry last updated: Jul 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting