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OpenTrials
Completed

NCT Number: NCT00776932

Chronic Knee Pain Study

Specific Aims: 1) To examine differences between AA and white patients with knee OA in willingness to consider knee joint replacement. 2) To examine the relationship between socio-cultural factors and patient willingness to consider joint replacement. 3) To examine how demographic, socio-cultural, and clinical factors mediate the relationship between race and patient willingness. 4) To examine the relationship between patient willingness and referral to orthopedic care for knee OA (secondary aim).

Experimental design/Methodology: A cross-sectional survey study design will be used to examine socio-cultural and clinical factors that may vary by race/ethnicity and may be determinants of willingness to consider joint replacement as a treatment option. Patients with symptomatic and radiographic knee OA from the primary care clinics will be surveyed. Only individuals with knee OA of sufficient severity that would be considered candidates for joint replacement will be included. Analytic strategies include ordinal logistic regression, path analysis, and regression trees.

Subject population: The study sample will consist of approximately 133 African American and 419 white patients with OA of the knee in a primary care setting.

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Key information

Age range

50 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Pittsburh Arthritis Research Center

Pittsburgh, Pennsylvania, 15213, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • over age 50
  • chronic knee pain
  • radiographic evidence of knee OA

Exclusion criteria

  • previous joint replacement
  • inflammatory arthritis

Treatment and study plan

Primary outcomes

  1. Compared to whites, AAs with knee OA will be less willing to consider joint replacement. Logistic regression will be used to model the categorical measure of willingness, if preliminary analyses indicate dichotomizing this measure.

    Time frame: Study Completion

Sponsors and collaborators

Lead sponsor

University of Pittsburgh

Other

Collaborators

  • National Institutes of Health (NIH)

Registry information

Official study title

Disparity in Joint Replacement: Pathway to Intervention

Acronym: JRPIT

Important dates

Study start
2007
Primary completion
2011
Study completion
2013
First posted
Oct 22, 2008
Registry last updated
May 27, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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