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Completed

NCT Number: NCT01113203

Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure

The study aimed to evaluate the chronic and acute effects of high-intensity resistance training on blood pressure and its hemodynamic and neural determinators in healthy normotensive older subjects.

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Key information

Conditions

Blood Pressure

Age range

60 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

School of Physical Education and Sport, University of São Paulo

São Paulo, 05508-030, Brazil

About this study

To investigate the chronic and acute effects of resistance training on blood pressure and its hemodynamic and neural determinators in elderly, 24 healthy normotensive older subjects were randomly divided into 2 groups: trained and control. The trained group was submitted a progressive high-intensity resistance training. Before and after 16 weeks, as well as, before and after the one training session, blood pressure (clinic and ambulatory), cardiac output (CO2 rebreathing), and autonomic modulation (spectral analysis of heart rate and blood pressure variabilities) were measured

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 60 to 80 years
  • Normotensives
  • Nonactive

Exclusion criteria

  • Cardiovascular disease
  • Cardiovascular medication
  • Orthopedic problems

Treatment and study plan

Resistance training

Behavioral

Progressive high intensity resistance training performed twice a week for 16 weeks, and achieving in 7 exercises for the main muscles, the protocol of 4 sets of 6RM and 2 of 4RM.

Other names: strength training, weight training

Primary outcomes

  1. blood pressure

    Time frame: 16 weeks

    Blood pressure was measured by auscultatory, oscillometric and photoplethysmographic device

Secondary outcomes

  1. cardiovascular hemodynamics

    Time frame: 16 weeks

    cardiac output (CO2 rebreathing technique)

  2. cardiovascular autonomic modulation

    Time frame: 16 weeks

    Spectral analysis of heart rate and blood pressure variabillity

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Collaborators

  • Associacao Fundo de Incentivo a Psicofarmcologia
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
  • Delboni Auriemo
  • Federal University of São Paulo
  • Fundação de Amparo à Pesquisa do Estado de São Paulo

Registry information

Acronym: RTBP

Important dates

Study start
2008
Primary completion
2008
Study completion
2008
First posted
Apr 29, 2010
Registry last updated
Apr 29, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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